Endocrine Pathology Flashcards
What are the various Pituitary Syndromes?
gigantism; dwarfism; acromegaly; diabetes insipidus
What are the various thyroid syndromes?
hyper/hypothyroidism; thyroiditis; thyroid cancer
What are the various Parathyroid syndromes?
hyper/hypoparathyroidism
What are the various adrenal syndromes?
addison’s; cushing’s; conn’s
What are the various pancreatic syndromes?
diabetes mellitus Type I and II
What is gigantism?
overgrowth of long bones via GH excess during childhood
What causes dwarfism?
too little GH production
What causes acromegaly?
too much GH during adulthood
What are the treatment options for acromegaly?
radiation, surgical removal of pituitary; hormone replacement
What is a common complaint of a patient with acromegaly?
bone/backpain due to calcification of anterior longitudinal ligament
What is Diabetes Insipidus?
disorder of the post. pituitary causing an ADH deficiency
What are common S&S of Diabetes Insipidus?
polydipsia; polyuria/nocturia; dehydration
Neurogenic vs. Nephrogenic Diabetes Insipidus?
Neuro: defect synthesis or release of ADH
Nephro: kidneys don’t respond to ADH (excessive urination leading to excessive thirst)
Diabetes insipidus vs mellitus?
Insipidus: pituitary gland; dehydration; ADH deficiency
Mellitus: pancreas; insulin insufficient; increased appetite
What are the PT implications of Diabetes Insipidus?
increased BP; GI Irritability; contraction of smooth vascular muscle
What is hyperthyroidism?
imbalance caused by overproduction of thyroid hormone (graves); will present with protruding eyes (exopthalmos)
What are the clinical manifestations of hyperthyroidism?
heat intolerance; will look like a student during finals (up all night, too much coffee, restless, nervous, anxiety, palpitations)
What will hyperthyroidism do to vital signs?
it will increase them (bp, HR, RR)
What is the pathway of hyperthyroidism?
hypothalamus cascades down through pituitary gland to decrease TSH causing excess T3 and normal T4
What are treatment options for hyperthyroidism?
radiation; surgery; hormone replacement and beta blockers