Endocrine (Hormone) System Flashcards
Role of Endocrine System
to maintain homeostasis (along with the nervous system)
Homeostasis
process by which a constant internal environment is maintained despite changes in the external environment
Endocrine vs Nervous System
Nervous system: quick system, adjusting rapidly to changes
Endocrine: slower system, long term control over homeostasis
Hormones
Chemicals produced in one part of the body by the endocrine system to affect distant cells.
- act as regulators (speed up/slow down certain processes)
- cells have receptors for certain hormones only
Non- Target Hormones
Affect many cells throughout the body
ex. insulin causes many cells to absorb glucose
Target Hormones
Affect specific cells/tissues only
ex. gastrin affects the stomach only
Tropic Hormones
Activate other endocrine glands to release other hormones.
ex. TSH from the pituitary activates the thyroid gland to release thyroxine
Non- Tropic Hormones
Stimulate other tissues that are not endocrine.
ex. Epinephrine affects the heart, blood vessels, diaphragm, air-ways, etc.
Steroid Hormones
-Made from cholesterol
-Fat soluble
-longer lasting effects
Act from inside the cell by diffusing into the specific cell and can be taken orally by patients (will not be digested by stomach)
ex. thyroxine, testosterone,
Protein Hormones
-Composed of proteins, peptides, or amino acid derivatives
-Water soluble
-aka “non-steroidal hormones”
Act from outside the cell, binding to receptor sites which activate enzymes to carry out specific functions
-CANNOT be taken orally
ex. ADH, hGh
Regulation of Hormones
Hormones are regulated through NEGATIVE feedback mechanisms.
Hypothalamus
Maintains homeostasis.
- controls the pituitary gland via nerves and hormones
- produces releasing hormones (factors)
- produces ADH and oxytocin
Posterior Pituitary
DOES NOT MAKE HORMONES
- made of nervous tissue
- stores and releases hormones made by the hypothalamus (ADH and oxytocin)
- hypothalamus sends these hormones by neurosecretory cells
Anterior Pituitary
MAKES ITS OWN HORMONES
- made of glandular tissue
- makes and stores hormones
- releases hormones via releasing hormones from the hypothalamus
- hormones: TSH, ACTH, PRL, hGH, FSH, LH
ADH (hormone)
Antidiuretic Hormone= Vasopressin
- stimulates water reabsorption in kidneys
- produced by hypothalamus, released by pos. pituitary