Endocrine (Gram) Flashcards
1
Q
Dermatologic differential diagnosis: PAIN 4 ME
A
- Parasitic (fleas, scabies, demodex)
- Allergic (environment, food, parasite, contact(
- Immune mediated/Idiopathic/Idunno
- 4 - other misc.
- Microbial (bacteria, yeast, dermatophyte)
- Endocrine (endogenous)
2
Q
General concepts of endocrine disease
A
- Middle aged animals
- Alteration in hair coat (alopecia, texture)
- Underlying non-pruritic dz responsible for recurrent skin and ear infections (which can itch)
3
Q
Primary hypothyroidism
A
Thyroid
- Idiopathic atrophy
- lymphocytic thyroiditis
- neoplasia
4
Q
Secondary hypothyroidism
A
Pituitary gland
5
Q
Tertiary hypothyroidism
A
Hypothalamus
6
Q
Sick euthyroid
A
Hypothyroidism induced by medications or just being sick
7
Q
T4
A
- most often measured clinically (important for testing)
- made directly from the thyroid in higher amounts than T3
- not as biologically active as T3
8
Q
T3
A
- more metabolically active than T4
- mainly intracellular
- 10-20% produced directly from thyroid
- 80-90% derived from T4
9
Q
Thyroid physiology
A
- Turnover rate is higher in dogs than humans
- replacement dose needs to be much higher
- Thyroid hormones bind to proteins
10
Q
Functions of thyroid hormone
A
- Growth
- Protein synthesis
- Lipid metabolism
- Carb metabolism
- Hematopoiesis
- Reproduction
11
Q
Low thyroid effect on growth
A
Alopecia
12
Q
Low thyroid effect on protein metabolism
A
Altered metabolism
13
Q
Low thyroid effect on lipid metabolism
A
Elevated cholesterol
14
Q
Low thyroid effect on hematopoiesis
A
Mild anemia
15
Q
Low thyroid effect on reproduciton
A
Decreased
