Endocrine Formative Assessment 20/12/19 Flashcards
Which of the following is not under the control of the pituitary gland? A. Thyroid B. Adrenal cortex C. Adrenal medulla D. Testis E. Ovary
C. Adrenal Medulla
Which of the following statements is false? A. The pituitary gland lies in the sella turcica B. The weight of the pituitary gland is around 0.5g C. ACTH is secreted from the pituitary during stress D. The pituitary regulates calcium metabolism E. The anterior and posterior pituitary are distinct on an MRI scan
D. The pituitary regulates calcium metabolism
In men all the following are mainly produced in the adrenal cortex except? A. DHEAS B. Testosterone C. Aldosterone D. 17-OH progesterone E. Androstenedione
B. Testosterone
Which of the following regarding AVP is false? A. AVP levels have a linear relationship with serum osmolality B. is produced in the pituitary gland C. stimulates reabsorption of water in the collecting duct of the nephron D. in hypotension baroreceptors predominantly activate ADH production and secretion E. Further AVP production is no longer effective once urine osmolality has reached a plateau
B. is produced in the pituitary gland
Where is growth hormone’s main site of action to stimulate IGF1 release? A. Bone B. Liver C. Adrenal cortex D. Muscle E. Pancreas
B. Liver
The following are typical features of excess growth hormone secretion except? A. Polyuria B. Joint pains C. Sweating D. Hypotension E. Headaches
D. Hypotension
The following hormones all have a circadian rhythm except? A. Cortisol B. Testosterone C. DHEA D. 17OH progesterone E. Thyroxine (T4)
E. Thyroxine (T4)
Typical features of cortisol deficiency include the following except? A. Hypotension B. Muscle aches C. Weight loss D. Hyperglycaemia E. Lethargy
D. Hyperglycaemia
A 38 year old lady presented with weight gain, menorrhagia and constipation. She is most likely to be suffering from? A. Cushing’s syndrome B. Addison’s disease C. Primary hypothyroidism D. Graves disease E. Acromegaly
C. Primary hypothyroidism
Which test would you likely want to perform in a patient with proximal muscle weakness, purple striae and thin skin? A. Synacthen test B. Overnight dexamethasone suppression test C. Insulin tolerance test D. Glucagon test E. Skin allergy tests
B. Overnight dexamethasone suppression test
A 24 year old girl presented with hirsutism, oligomenorrhoea and acne. What test would you likely carry out from the ones below? A. Ultra sound adrenals B. Ultra sound ovaries C. MRI ovaries D. CT scan adrenals E. Prolactin
B. Ultra sound ovaries
A 54 year old gentleman presented with hyponatraemia. All the following conditions need excluding before confirming SIADH except? A. Hypothyroidism B. Hypervolaemia C. Euvolaemia D. Adrenal insufficiency E. Diuretic use
C. Euvolaemia
A 66 year old gentleman had a serum sodium of 124 mmol/l, serum osmolality 265 mmol/l and a urine sodium of 52 mmol/l. What would you like to perform first? A. Chest X-ray B. CT brain C. Skin turgor and jugular venous pressure test D. Thyroid function tests E. Synacthentest
C. Skin turgor and jugular venous pressure test
The following are most likely causes of SIADH except?
A. Multiple sclerosis
B. Lung abscess
C. Subdural haemorrhage
D. Lymphoma
E. Cerebrovascular accident
A. Muliple sclerosis
A 28 year old presented with a microprolactinoma? What is the most unlikely symptom?
A. Galactorrhoea
B. Oligomenorrhoea
C. Decreased sexual appetite
D. Headaches
E. Visual field defects
E. Visual field defects
A 65 year old lady is diagnosed with SIADH. Her sodium is 123mmol/l. What is your first line of management?
A. If she is symptomatic I will treat with fluid restriction
B. If she is asymptomatic I will treat with hypertonic saline
C. If she is asymptomatic I will treat with fluid restriction
D. If she is asymptomatic I will repeat the sodium level the next day
E. If she is asymptomatic I will give normal saline
C. If she is asymptomatic I will treat with fluid restriction
