endocrine/ears/eye Flashcards
What were the findings regarding hemostasis in hyperthyroid cats compared to euthyroid controls? * Moreno, JVIM 2024.
Hyperthyroid cats showed increased clot amplitude, clot firmness, and faster coagulation times.
This was assessed using two viscoelastic assays and platelet aggregometry.
What is the survival time comparison between thyroidectomy and methimazole treatment for hyperthyroid cats? * Naito, JAVMA 2024.
Thyroidectomy: 1893 days (5 years) vs Methimazole: 730 days (2 years).
Recurrence rates were 13% for thyroidectomy and 27% for methimazole.
What was the most common cause of death for cats treated with methimazole and thyroidectomy? * Naito, JAVMA 2024.
Methimazole: heart failure, Thyroidectomy: chronic kidney disease (CKD).
This highlights the differing risks associated with each treatment.
What was the cure rate for ultrasound-guided minimally invasive parathyroidectomy in dogs with primary hyperparathyroidism? Young, vet surg 2023
Cure rate: 93%.
This is comparable to the reported cure rate of ~95% for bilateral neck exploration.
What percentage of dogs experienced postoperative hypocalcemia after ultrasound guided MIS parathyroidectomy? Young, vet surg 2023
15%.
This rate is lower than previously reported rates of ~36-60%.
What was the median survival time (MST) for dogs undergoing thyroidectomy for thyroid tumors? * Enache, JVIM 2023.
MST: 802 days (2 years).
Metastasis occurred in 8% of cases.
What association was found between thrombosis and risk of death in dogs with thyroid tumors? * Enache, JVIM 2023.
Thrombosis was associated with an increased risk of death (27%).
Nonfollicular carcinoma and chemotherapy administration were also linked to an increased risk of cancer-related death.
What was the recommendation regarding surgical exploration for dogs with parathyroid masses? * Burkhardt. VS 2021.
Bilateral cervical surgical exploration is recommended.
A parathyroid mass ≥ 8.0 mm was suggestive of malignancy (carcinoma).
What was the MST for dogs with parathyroid carcinomas after surgical treatment? * Erickson, JAVMA 2021.
One-year survival rate: 84%.
MST = 2yr
The median survival time was 2 years, with preoperative hypercalcemia resolving in 93% postoperatively.
What percentage of dogs with thyroid carcinoma showed metastasis to lymph nodes? * Skinner, Vet surg 2021.
Metastasis occurred in 45% of cases.
It was common in deep cervical and medial retropharyngeal lymph nodes.
What were the most common clinical signs (CS) of functional thyroid tumors in dogs? * Frederick, JAVMA 2020.
PU/PD and weight loss.
Golden Retrievers and Labrador Retrievers were the most common breeds affected.
What was the mortality rate associated with unilateral thyroidectomy in dogs? * Reagan, JAVMA 2019.
Mortality rate: 2%.
The complication rate was 20%, with hemorrhage and aspiration pneumonia being the most common issues.
What was the median survival time (MST) for cats undergoing surgical treatment of primary hyperparathyroidism? * Singh, vet surg 2019.
MST: 1109 days (3 years).
Most common tumors were parathyroid adenoma (62%) and parathyroid carcinoma (22%).
What was the impact of using a vessel-sealing device (VSD) during thyroidectomy in dogs? * Lorange, JAVMA 2019.
Shorter operative times without significantly affecting complication rates or hospitalization times.
This suggests VSD may be a beneficial tool in thyroid surgeries.
True or False: Preoperative serum total calcium (tCa) and ionized calcium (iCa) concentrations were predictive of postoperative hypocalcemia. * Milovancev, JAVMA 2013.
False.
No correlation was found between preoperative serum calcium levels and postoperative outcomes.
Fill in the blank: The most common tumors in cats with primary hyperparathyroidism are parathyroid _______ and parathyroid carcinoma. * Singh, vet surg 2019.
adenoma.
Parathyroid adenomas accounted for 62% of cases.
What was the agreement percentage of ultrasonography and surgery in identifying parathyroid pathology? * Burkhardt. VS 2021.
65% number of glands, 72% for side identification
Surgery correctly identified abnormal glands in 78% of cases.
What parathyroid mass size is suggestive of malignancy? * Burkhardt. VS 2021.
≥ 8.0 mm
This indicates a potential carcinoma.
What preoperative ionized calcium level increases the risk for postoperative hypocalcemia? * Burkhardt. VS 2021.
≥ 1.75 mEq/L
This level results in a 7.5x increased risk for developing hypocalcemia post-surgery.
What percentage of dogs developed hypocalcemia postoperatively in the study? * Burkhardt. VS 2021.
47%
This highlights the significance of monitoring postoperative calcium levels.
What surgical approach is recommended for dogs undergoing parathyroidectomy? * Burkhardt. VS 2021.
Bilateral cervical surgical exploration
This is recommended to effectively address parathyroid pathology.
What were the common clinical signs (CS) of parathyroid carcinomas in dogs? * Erickson, JAVMA 2021.
- PU/PD
- PL paresis
- Lethargy
- Hyporexia
These signs indicate potential parathyroid issues.
What is the incidence of postoperative hypocalcemia in dogs after surgery for parathyroid carcinoma? * Erickson, JAVMA 2021.
34%
Monitoring is crucial due to the significant occurrence of this complication.
What is the median survival time (MST) for dogs with parathyroid carcinomas? * Erickson, JAVMA 2021.
2 years
The 1-year survival rate is reported at 84%.
What percentage of functional thyroid tumors in dogs are malignant? * Frederick, JAVMA 2020.
85%
What is the metastatic rate for malignant functional thyroid tumors in dogs? * Frederick, JAVMA 2020.
4%
What is the median survival time (MST) for dogs with functional thyroid tumors vs malignant thyroid vs benign ? * Frederick, JAVMA 2020.
1,072 days (35 months / 3 years)
MST: malignant thyroid tumors = 970 days (32 months / 2.5 years) vs benign = 1,072 days (35 months / 3 years)
What is the most common type of adrenal tumor associated with spontaneous hemorrhage in dogs and cats? * Traverson, JAVMA 2023.
Adrenocortical neoplasia and pheochromocytoma
Adrenocortical neoplasia: malignant (41%) vs benign (12%), pheochromocytoma (38%)
What is the overall mortality rate for adrenal tumors treated by adrenalectomy after spontaneous hemoabd? * Traverson, JAVMA 2023.
21%
Complications associated with the procedure are reported at 42%
What is the median survival time (MST) for dogs after adrenalectomy for adrenal tumors for spontaneous hemoabdomen? * Traverson, JAVMA 2023.
574 days (1.5 years), 900 days (2.5 years) if censoring short-term mortality
What is the median maximum tumor diameter for dogs undergoing BSSLA? * Farrell, JAVMA 2023
2.3-2.6 cm
What percentage of dogs undergoing adrenalectomy are considered hypercoagulable? * Mitsui, JAVMA 2023.
53%
0% were hypocoagulable