Endocrine diseases

Question 1

What is cushings caused by?

Answer 1

(too much cortisol)
- functional pituitary tumour
-functional adrenal tumour
latrogenic (cause by medication)

Question 2

what glands are involved wuith cortisol and adrenaline?

Answer 2

-hypothalomus
-pituitary
-adrenal cortex

Question 3

complications of cushing disease?

Answer 3

-diabetes
-uti
-panceaitis
-systematic hypertension

Question 4

How is cushing diagnosed

Answer 4

-heamotology (eosinopeania
-urinealysis
-biochemistry
radiology
-ultrosonograophy for adrenal tumour
- acth stimulation test
-lddst

Question 5

What is a ATCH stimulation test?

Answer 5

-pdh = exagerated responce to atch (cortisiol levels high
-adh - no responce at all

Question 6

WHat is a low dose dexamethasone supprestion test?

Answer 6

• dexamathine is added and cortisol levels are measured in responce
• pdh- dogs have a high basal level which then dips and regains
  adh- dogws have a high basal level that dips less then regains
  normal- dogs have no change in cortisol

Question 7

what is the treatment for cushings?

Answer 7

-pdh
trilosone (pdh) - inhibits cortisol
milotone -chemotherapy
ketoconzole - suppresses steriod genisis
-radiation treatment
bilateral adrenalactomy
-adh
-unilateral adrenalectomy
tilosone/ mitotane at high doses

Question 8

What is canine hypoadernanocortisium/ addisons?

Answer 8

lack of mineralcorticiod and glucocorticiod

Question 9

what is addisions caused by?

Answer 9

-destruction of adrenal cortex
-atch deficency
-latrogenic

Question 10

what clinical signs can be seen in the acute for of addisions diesea

Answer 10

• vomiting
  -anorexia
  hypovalimia (low extra cellular fluid)
  bradycardia (slow heart rate)
• vauge signs

Question 11

how is addisions disease diagnosed

Answer 11

-urinalysis
heamotology 9eosophilia)
biochemistry (prerenal azotaemia- build u of nitrogen)
radiology -miocardia
- ecg - heart
-atch stim test

Question 12

Ehat is the treatment for addisions disease?

Answer 12

• accute =fluids, glucacorticiod and mineral corticiods suplimentation) (mineral cordicoids are not injectable)/ monitor unine output
• chronic disease = mineralcorticiod tablets, table salt, gluticorticiods initally and at times of stress
  ad-lib water
  monitor potasium nitrogen and clorine levels within the blood