Endocrine Conditions Flashcards
List at least 4 symptoms of Hyperthyroidism?
- Weight loss
- nervous/anxious
- tachycardia
- heat intolerance
- isomnia
- tremor/muscle weakness
- goitre
Explain what Cushing’s Syndrome is
Hypercortisolism
It is the signs and symptoms of excessive cortisol (glucocorticoids hormones) levels in the blood.
Causes:
Can be caused by steroids or body makes too much cortisol
Conditions resulting from this;
Obesity
High BP
diabetes
Osteo
Management:
Meds, surgery, radiotherapy
Outline the pathophysiology of at least three (3) signs or symptoms associated with excess cortisol levels (Cushing syndrome).
- Central Obesity - Excess cortisol promotes breakdown of fats in visceral adipose which enlarge and mulitiple in central body. Also inhibits peripheral glucose uptake, leading to increased fat deposition, abdomen, back hump and moon face.
- Muscle weakness/wasting - Cortisol increases protein breakdown in muscle cells
- Skin changes - cortisol inhibits collagen formation by fibroblasts leading to thinning of skin and striae, and supresses immune response, impaired wound healing
What do the adrenal glands take care of (according to Ross’s lecture)?
G lucocorticoids - SUGAR
A ldosterone - SALT
T estosterone/Estrogen - SEX
Explain an example of a cause of Hyperthyroidism
Graves Diseases - autoimmune disorder with high T3 & T4 hormone levels
S&S:
Goitre
bulging eyes
Management:
Reduce hormone levels and achieve symptom control. Meds like antithyroid to interfere with TH production
