Endocrine: buzzwords/diseases

Question 1

secondary disorder labs are ______ while primary disorder labs are____

Answer 1

secondary= same direction

primary=opposite direction

Question 2

labs for TSH-secreting pituitary adenoma

Answer 2

SECONDARY DZ
high TSH
high Free T4/T3

Question 3

basic labs for Cushings disease (pituitary adenoma)

Answer 3

Secondary dz
ACTH high
cortisol High

Question 4

Hypopituitarism labs

Answer 4

secondary dz

• low target organ hormones
• low pituitary hormones

Question 5

labs for graves dz

Answer 5

PRIMARY dz— thyroid is the issue

• free t4/t3
• low tsh

Question 6

basic labs for toxic goiter

Answer 6

primary dz

• free t4/t3
• low tsh

Question 7

labs for toxic adenoma

Answer 7

primary dz

high free t4/t3
low tsh

Question 8

Hashimotos dz labs

Answer 8

primary dz

• low t4/t3
• high tsh

Question 9

thyroiditis

Answer 9

low free t4/t3

high tsh

Question 10

addisons disease labs

Answer 10

adrenal gland is the primary problem

low cortisol and high ACTH

Question 11

adrenal adenoma basic labs

Answer 11

primary dz
high cortisol
low ACTH

Question 12

tertiary disorders ____ is the problem

secondary disorders ____ is the problem

primary disorders ____ is the problem

Answer 12

tertiary=hypothalamus

secondary=pituitary gland

primary=target organ

Question 13

Adrenal Crisis aka Adrenocortical insufficiency aka addisonian crisis

• what is this
• preicipated by
• etiologies —MCC
• cm
• labs/diagnosis

Answer 13

• *sudden worsening of symptoms in diagnosed or undiagnosed chronic adrenal insufficiency
• *precipitated by a “stressful” event (illness, surgery, trauma, volume loss, hypothermia, etc

Etiologies

• abrupt withdrawal of glucocorticoids (w/o tapering) MCC
• bilateral adrenal infarction (hemorrhage)

CM
-shock mc s/s–>hypotension, hypovolemia, nonspecific symptoms

Diagnosis/labs

• hyponatremia
• hyperK
• hypoglycemia
• cortisol and aldosterone (confirms diagnosis)