Endocrine and Reproductive Systems Flashcards

1
Q

Hormones are _______________

A

Chemicals, secreted by one cell group, that travel through the bloodstream to act on targets

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2
Q

Neurotransmitters vs hormones. What are the traits of neurotransmitters?

A
  1. Secreted by neurons
  2. Travel short distances through the synapse
  3. Travel to precise destinations (receptors on the postsynaptic neuron)
  4. Rapid messages
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3
Q

Neurotransmitters vs hormones. What are the traits of hormones?

A
  1. Secreted by endocrine glands
  2. Travel long distances through the blood
  3. Spread throughout the body, but only picked up by cells with the proper receptors
  4. Slower messages
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4
Q

Classic early endocrinology study by ____________________ suggested the nature of hormones

A

Berthold in 1849

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5
Q

What were the finding of the nature of hormones by Berthold in 1849?

A
  1. Uncastrated roosters had secondary sex characteristics
  2. Castrated roosters had no secondary sex characteristics
  3. Roosters with testes reimplanted in abdomen (not connected by nerves)….
    -had secondary sex characteristics
    -indicated signal traveling through blood- hormone
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6
Q

Endocrine is the system that _____________________

A

Secretes hormones into the blood stream

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7
Q

Glands are ___________________

A

Organs that secrete substances, such as hormones

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8
Q

Neuroendocrine is when _____________

A

Signaling molecules are secreted by a neuron into the blood, where they function as hormones

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9
Q

How do peptide hormones (proteins or peptides) work?

A

They bind extracellular receptors

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10
Q

What are steroid hormones synthesized by?

A

Cholesterol

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11
Q

What are amino acid-derived hormones synthesized from?

A

Tryptophan or tyrosine

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12
Q

What do amino acid-derived hormones bind?

A

-Some bind cell membrane receptors (similar to peptide hormones)
-Some bind intracellular receptors (similar to steroid hormones)

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13
Q

Hormones are regulated by _______________________

A

Negative and positive feedback loops

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14
Q

Negative feedback loops _______________

A

Hormone inhibits further hormone secretion, and it maintains homeostasis

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15
Q

Example of negative feedback loops is when __________

A

Thyroid hormone inhibits production of thyroid hormone

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16
Q

Positive feedback loops _________________

A

are rare, and hormone release causes additional hormone release, and it amplifies signaling

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17
Q

Example of positive feedback loop is when ____________

A

Oxytocin release leads to uterine contractions, which cause additional oxytocin release

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18
Q

Thyroid hormones, produced by a butterfly-shaped gland in your _________ increase ___________________

A

-Neck
-Alertness and metabolism

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19
Q

The manufacturing of thyroid hormones depends on the ________________ and without it, the thyroid swells in an attempt to produce more __________ (called a goiter)

A

-Supply of iodine
-Iodine

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20
Q

The pineal gland is a

A

Single gland on top of the brainstem

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21
Q

What does the pineal gland secrete?

A

An amino acid-derived hormone, melatonin, almost exclusively at night.

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22
Q

Melatonin provides a signal that _________________

A

Tracks day length and the seasons

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23
Q

Where are the adrenal glands located and what do they do?

A

They are at the top of each kidney and secrete hormones

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24
Q

In mammals, the outer 80% of the gland is the _____________, and the core 20% is the ________________

A

-Adrenal cortex
-Adrenal medulla

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25
The adrenal medulla releases two hormones which are _____________________
Epinephrine (adrenaline) and Norepinephrine (noradrenaline)
26
Epinephrine (adrenaline) and norepinephrine (noradrenaline) are controlled by what system?
Sympathetic nervous system
27
Epinephrine (adrenaline) and norepinephrine (noradrenaline) are activated rapidly after __________
Stress occurs
28
The hypothalamic-pituitary-adrenal (HPA) axis is a ________________________________
Neuroendocrine system that responds to stress through hormone release
29
The hypothalamic-pituitary-adrenal (HPA) axis is activated __________________
Minutes to hours after stress occurs
30
The hypothalamic-pituitary-adrenal (HPA) axis end result is ___________________
The production of the stress hormone cortisol from the adrenal cortex
31
Cortisol is __________________
Secreted from the adrenal cortex during stress
32
What are the effects of cortisol?
1. Promotes “pro-survival” processes in the body 2. Increased blood pressure 3.Increased blood glucose 4.Inhibits “non-survival” processes 5.Decreased immunity 6. Decreased sexual behavior
33
Aldosterone is secreted from the _____________
Adrenal cortex
34
Aldosterone is ________________ and it _______________
- A steroid hormone which acts on the kidneys to retain sodium - Increases blood pressure
35
The pituitary gland releases important hormones and has two main parts which function separately that are called the ________________ and _________________
- Posterior pituitary - Anterior pituitary
36
Oxytocin “the love hormone“ functions in ___________________
1.Reproductive/ parenting behavior (bonding) in both biological sexes 2. Uterine contraction 3. Milk letdown reflex
37
Vasopressin (anti-diuretic hormone, or ADH) is released by __________________ and __________________
-The posterior pituitary -Increases blood pressure through water retention
38
Prolactin does what in females and males?
-In females: stimulates lactation and parental behavior -In males: affects sexual desire
39
Growth hormone (GH) ___________________________
Stimulates growth by acting on receptors in the liver, muscle, and bone
40
Psychosocial dwarfism is a _________________________
Failure to grow caused by stress early in life
41
Stress and sleep deprivation can interfere with ____________ and its normal effects on __________
-GH release -Growth
42
Where do reproductive hormones originate from?
Hypothalamus/anterior pituitary
43
In males, follicle-stimulating hormone (FSH) stimulates _________________________
Sperm maturation in Sertoli cells of the testes
44
In males, luteinizing hormone (LH) stimulates ______________________________
Testosterone production in Leydig cells of the testes
45
Testosterone is one of many male hormones called __________ and they _____________________
-Androgens -1. Maintains spermatogenesis (sperm cell development) 2. Controls changes in the male body that become apparent in puberty: -Voice change -Hair growth -Development and maintenance of genitalia -Sex drive
46
In females, follicle-stimulating hormone (FSH) stimulates ______________________
Egg-containing follicles to develop
47
In females, luteinizing hormone (LH) stimulates _______________________________
Follicles to form the corpora luteum (temporary endocrine structure in ovaries)
48
The ovarian cycle is related to _____________
Egg release
49
The menstrual cycle is related to ___________________
Uterine lining (endometrium) thickness
50
Menstrual phase is a _____________________________
Shedding of the uterine lining when estrogen/progesterone levels are low
51
Proliferative phase is a ________________________________
Growth of the uterine lining due to estrogen produced by ovarian follicles
52
Secretory phase is a
Maintenance phase with increased blood flow/secretions due to progesterone produced by the corpus luteum
53
Many birth control pills work by administering exogenous amounts of ____________________________
Estrogen/progesterone
54
Gametogenesis is the process of ______________________
Producing sperm cells and egg cells (gametes)
55
Gametogenesis process must include _____________________
Meiosis to generate haploid gametes from diploid somatic cells
56
Sexual reproduction relies on______________ where two haploid gametes combine to generate a ________________
-Fertilization -Diploid zygote
57
Spermatogonial cells are _________________________
Self-renewing (mitosis!) near the outside of the seminiferous tubules
58
Sperm carries ______________________
X or Y chromosome
59
Y chromosome has SRY gene, which turns on other genes on other chromosomes to cause anatomically _________________ and in absence of SRY, anatomically ______________
-Male development -Female development
60
Altered expression of SRY, SRY receptors, or many other genes under SRY or sex hormone control can cause ________________________________________
Anatomic differences from chromosomal predictions, including intersex development.