Endocrine Flashcards

1
Q

What three glands are produced with thyroid hormones?

A

T3,t4, calcitonin

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2
Q

What does calcitonin do?

A

Decrease cal levels putting from blood to bone

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3
Q

What makes hormones

A

Iodine

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4
Q

What do thyroid hormones do?

A

Provide energy

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5
Q

Hyperthyroidism

A
S/s GRAVES / too much energy 
Nervous
Irritable 
Short attention span 
Weight down 
Appetite up 
Exopthalmus 
GI fast 
BP/BPM up 
Arrythmia 
Increase in thyroid 
Diagnosis 
T4 is 
Tsh 
Thyroid scan - must discontinue 1 week and restart in 6 weeks 
Ultrasound/MRI/CT 
Txt 
Anti thyroid methimazole 
Stops making thyroid 
Used for preop 
Euthyroid

Iodine
Decrease size of gland
Use straw why? With milk/juice

Beta blockers 
LOL propanol 
Decrease myocardial contractility 
Decrease HR/BP Anxiety 
*contra for diabetics and asthmatics 
Radioactive therapy 
1 dose 
Po -r/o pregnancy 
Destroys thyroid cells 
Stay away from babies 1 week no contact 1wk 

*thyroid storms

Surgery thyroidectomy
Priority* hemorrhage
Reporting pressure
Check bleeding on incision

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6
Q

How to care for thyroidectomy pt2?

A
Assess for bleeding at incision 
Laryngel damage? How? 
Potential paralysis requires trach 
Trach set at bedside 
Swelling 
Hypocalcemia -assess parathyroid removal theyre  not sedated they are rigid 

Teach:
Support neck
Personal items close
Increase calories post op

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7
Q

Hypothyroidism

A
S/s
No energy 
Tired
Slow speech 
Weight increase
Gi slow 
Cold 
Ammenorrhea

Diagnosis
t4 decreased
Tsh increased

Txt
Levothyroxine empty stomach
Tend to have CAD because of increased LDL
Forever on meds

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8
Q

What is a parathyroid problem

A

Affects Ca

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9
Q

Hyperparathyroidism=hypercal=hypophos

A

Too much pth, sedated

Txt
Partial parathyroidectomy to decrease PTH
Monitor for hypocal (tight ridgid muscle)

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10
Q

Hypopara=hypocal=hyperphos

A

Too little pth, ca low, not sedated

Txt:
Iv ca
Pho binding drugs

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11
Q

What does your adrenal gland do?

A

Respond to stress with two parts,

adrenal cortext and adrenal meddulla

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12
Q

What does the adrenal medulla release

A

Epi and Norephi

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13
Q

What is a complication of adrenal medulla

A

Phenochromocytoma, which is a benign tumor that releases in boluses.
Familial

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14
Q

S/s of Phenochromocytoma?

A
Bp UP
HR UP
Palpitations Yes
Flushing and diaphoretic 
headache Yes
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15
Q

How to diagnose Phenochromocytoma?

A

Catecoline levels VMA/MN
24 hr specimen - throw away first void, keep last void
Avoid activities that increase nor and ephi
Surgery to remove tumors
*Avoid palpating abdomen as this can activate release and increase bp

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16
Q

Purpose of Adrenal Cortex?

A

Secretes hormones - gluccorticoids, mineralocorticoids, and sex hormones

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17
Q

What does the gluccorticoids do in a/cortex?

A
Chnage your mood
alter defense mechanisms 
immunosupressed = risk for infection 
breaks down protein and fats - energy
inhibit insulin - hyperglycemic
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18
Q

What does mineralocorticoids / ald do?

A

Retain Na and H2o, and lose potassium

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19
Q

What does sex hormones do?

A

Hirsutism
Acne
Irreg Menstral cycle

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20
Q

What are the problems with Adrenal Cortex?

A
Not enough steroids
shock
hyperkalemia 
hypoglycemia
Addison's disease
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21
Q

What is addisons disease?

A

Not enough steroids.

S/S 
Extreme fatigue
nause/vo/diah
weightloss
hypotension 
confusion
decreased sodium potassium, hypoglycemia 
hyperkal
hyperpig
vitiligo
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22
Q

What is the treatment for addison?

A
Fight against shock
increase sodium 
processed fruit/broth
increase  i/o
Bp will likely be low, and losing weight/FVD

Meds
Corticosteriods - 2x a day split morning and evening
Fludocortisone acetate synthetic aldosterone
daily weight and bp monitored *monitor for Bp changes

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23
Q

What is addision crisis?

A

Sever hypotension and vascular collapse due to infection, emotional stress, and stopping steroids abruptly. b/sugar down.

24
Q

What is cushing’s ?

A

Too much steriods

25
S/s of cushings?
``` buffalo hump acne moon face lipolysis thin extremities hyperglycemia trucal obesity - gluccorticoids ``` Oil skin/acne, male/women traits - sex hormones High BP, CHF, weight gain , FVE - Mineralcorticoids
26
What would the pt with cushing be low/high of?
Potassium, and high cortisol levels in 24hr urine
27
What is txt for cushing?
adrenalectomy uni or both- if both lifetime replacement quite environment avoid infection diet pre-treatment increase K, decrease Na, Increase Protein, Increase Ca Often steroids decreases serum calcium - hence brittle bones
28
Type 1 diabetes
Little or no insulin diagnose in childhood autoimmune response first sign DKA, appears abruptly polyphagia, dipsia, uria
29
What is the patho of diabetes 1
Normal > insulin carry glucose -> blood-> cell TDB1 - Stay in blood > hypertonic > kidneys > polyuria Cells -> fat protein breakdown> ketones > acidotic ZAq
30
S/S OF DM1 ?
Polyuria - FVD - Shock Polydipsia Polyphagia
31
Tx of DM1?
insulin not orally
32
What is syndrome X?
``` waist 40in male, 35 women trigly 150 HDL< 40 M, 50 F Bp high This increases the risk for CVD in type 2 ```
33
Txt for DM2
Oral agents/ some take insulin how do they work> produce insulin -metformin because it reduces glucose production and enhances how glucose enters the body, but may be prescribed with combo meds or lantus
34
What is Ges Dm2?
Type 2 dm need more insulin 2-3x more screen at 1st prenatal visit, screen again at 24-48 wks
35
Complications of ges dm2
Babies have increased birth weight and hypogly
36
General treatment for dm2/dm1
Majority of diet from complex carbs, fats, protein high fibre will slow down glucose exercise, watch for hypoglycemia preworkout, exercise when sugar is high, same time same amount
37
What to do undergoing surgery radiologic procedure with dm1/2 clients?
Stop metformin and resume 48hrs
38
How is insulin determined?
Bodyweight , avg dose is 0.4-1.0 units until no more ketones in urine
39
When drawing up NPH remember
Draw clear first
40
What is standard IV given?
Reg Rapid acting
41
What is the goal for insulin?
Give before meal to keep glucose near to 3-7.22
42
Most common method of insulin is
Basal bolus - long acting and a rapid (aspart or novlog) A long acting is given 1 a day, rapid acting given before meals divided into doses and must eat, Snacks do not require basal/bolus Clients should eat when insulin is at its peak- meaning sugar is lowest
43
What is client teaching like for DM1/2
Blood sugar test a1c to collect info in the past 3-4 months | When sick or stress sugar increases, due to normal response to help fight stressor, rotate within sites first
44
Insulin infusion pumps
Are alternate daily injections, rapid acting, better control
45
What to do if someone is hypoglycaemic
Give 15g or simple carb follow 15-15-15 rule
46
Once sugar is up for hypogly what to do?
Give complex carbs
47
An unconscious dm1/2?
Is treated like a hypogly
48
Treating an unconscious you can give?
D50w, glucagon
49
What to teach to hypogly,
Eat Take insulin Know signs of hypogly Check glucose
50
What is a complication of diabetes?
DKA could be the first sign of diabetes too Anything can trigger it
51
What is the patho for dka?
Absent or inade insulin - sugar is high - 3ps - fat breakdown- kussmal - LOC down Little to no insulin leading to metabolic acidosis fat break down
52
What is treatment for DKA?
Hourly blood sugar IV insulin -watch for hypogly and hypotas ECG Hourly outputs Abg IVFs start w: NS then when bs goes down give D5W add potassium to IV
53
Whats hhnk?
Looks like dka | Enough insulin no breakdown of fat no kussmal breathing both are hypergly ajd dehydra but not acidosis for hhnk
54
What vascular problems for dm1/2
Diabetic retinopathy and nephropathy
55
What are complications w/ nephropathy?
Sexual problems Foot/leg : no harsh chem, clean btwn tows, use a mirror Neurogenic bladder incontinece and retention Gastroparesis delayed stomach emptying risk for aspiration Increased risk for infection