Endocrine Flashcards
1
Q
How does 21-hydroxylase deficiency present?
A
The #1 cause of congenital adrenal hyperplasia
- Unable to convert progesterone to deoxycorticosterone (So no aldosterone = electrolyte abnormalities = hypotensive)
- Unable to convert 17-OH-progesterone to deoxycortisol (So no cortisol = hypoglycemia)
- Ambiguous genitalia in females (due to excess testosterone)
2
Q
How does 17-alpha-hydroxylase deficiency present?
A
Excess aldosterone = hypertensive
