endocrine Flashcards
layers of adrenal cortex?
glomerulosa (outside)
fasciculata (middle)
reticularis (inner)
adrenal cortex derived from what embryological tissue?
mesoderm
adrenal medulla derived from what embryological tissue?
neural crest
makes aldosterone, regulated by RAAS?
zona glomerulosa
makes cortisol, regulated by ACTH and CRH?
zona fasciculata
makes sex hormones, regulated by ACTH and CRH?
zona reticularis
makes catecholamines, regulated by preganglionic sympathetic fibers?
adrenal medulla
what are chromaffin cells?
make up the adrenal medulla
MC adrenal tumor in adults vs kids?
adults: pheo
kids: neuroblastoma
what hormones does the ant pit secrete?
FSH LH ACTH TSH prolactin GH
what hormones does the post pit secrete?
vasopression
oxytocin
where does melanotropin come from?
intermediate lobe of pituitary
subunits of TSH/LH/FSH/hCG?
alpha: common subunit
beta: determines specificity
which cells make GH and prolactin?
acidophils
which cells make FSH, LH, ACTH, TSH?
basophils
B FLAT
where are vasopressin and oxytocin made?
hypothalamus:
supraoptic nucleus –> vasopressin
paraventricular nucleus –> oxytocin
neurophysis transport to post pit
where are the alpha/beta/delta cells located in the islets of langerhans?
alpha (glucagon) = peripheral
beta (insulin) = interior
delta (SST) = interspersed
