Endocrine Flashcards

1
Q

differences between endocrine and nervous system

A
1. time scale
nervous -ms
endocrine-hours/days
2. mechanism of communication
nervous- action potentials/ neurotransmitters
endocrine-hormones
3. strength of signal 
frequency- nervous
amount of signal- endocrine
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2
Q

autocrine signals

A

locally affect same cell type

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3
Q

paracrine signals

A

locally affect nearby cells

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4
Q

pheremones

A

secreted into environment to modify behavior and physio of other

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5
Q

How is secretion rate of hormones controlled

A

Negative feedback

  1. action of a substance other than hormone on endocrine gland
  2. neural control of endocrine gland
  3. control of secretory activity of one endocrine gland by hormone or neurohormone secreted by another endocrine gland
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6
Q

mechanisms of hormone release

A
  1. humoral - in response to changing levels of ions or nutrients
  2. neural: stimulation by nerves
  3. hormonal: stimulation received from other hormones
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7
Q

neoplastic hormone production

A

when nonendocrine tissue produces hormones

syndromes caused by this is called paraneoplastic syndromes

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8
Q

down-regulation

A

decrease in number of receptors due to prolonged exposure to high concentration of hormone

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9
Q

up-regulation

A

increase in number of receptors due to prolonged exposure to a low concentration of hormone

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10
Q

permisiveness

A

presence of hormone increase (or decreases) number of receptors for another hormone
(cooperative hormones)

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11
Q

Functions of endocrine system

A
  1. metabolism and tissue maturation
  2. ion regulation
  3. water balance
  4. immune system regulation
  5. heart rate and blood pressure regulation
  6. control of blood glucose and other nutrients
  7. control of reproductive functions
  8. uterine contractions and milk release
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12
Q

vasopressin function

A

acts on blood vessels: vasoconstriction

acts on kidneys: decrease urine volume, increase blood volume

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13
Q

osmoreceptors

A

specialized neurons of hypothalamus that monitor changes in intercellular osmolarity

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14
Q

baroreceptors

A

specialized neurons that sense change in blood pressure

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15
Q

when is vasopressin released

A

electrolytes increase
concentration of water decreases
blood pressure decreases

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16
Q

oxytocin

A

acts on uterus to stimulate contraction

17
Q

somatostatin

A

growth hormone-inhibiting hormone

18
Q

epinephrine

A

adrenaline

19
Q

where are catecholamine hormones secreted

A

medulla

20
Q

cortisol

A

regulate glucose metabolism and the immune system

21
Q

aldosterone

A

regulate salt and water balance

22
Q

cushing’s disease

A

chronically high levels of glucocorticoids like cortisol

unctontrolled catabolism of bone, muscle, skin and other organs

23
Q

Addison’s disease

A

loss of adrenal cortical function due to deficit in glucocorticoids

24
Q

tyrosine/iodide

A

primary ingredients for synthesis of thyroid hormones

25
Q

Graves disease

A

autoimmune overstimulation and growth of thyroid gland causes hyperthyroidism

26
Q

parathyroid hormone

A

cause osteoclasts to degrade bone and release Ca2+ into blood

27
Q

calcitonin

A

stimulates calcium deposit in bone by inhibiting osteoclasts

28
Q

where is calcium regulated from

A

thyroid gland release calcitonin

parathyroid glands release parathyroid hormone

29
Q

process of fracture repair

A
  1. hematoma formation
  2. fibrocartilaginous callus formation
  3. callus ossification
  4. bone remodeling
30
Q

location of glucose homeostasis

A

pancreatic islets (islets of langerhans)

31
Q

glucagon release and function

A

released by alpha cells causes catabolism of glucose when there’s a decrease in blood

32
Q

insulin release and function

A

released by beta cells causes anabolism of glucose when there’s an increase in blood

33
Q

hypoglycemia

A

oversecretion of insulin -> low glucose levels

34
Q

Type I diabetes

A

insulin dependent

Beta cells destroyed

35
Q

Type II diabetes

A

non-insulin dependent - decreased sensitivity to insulin