Endocrine Flashcards

1
Q

What causes crushing syndrome?

A

Steroids and ACTH releasing tumours

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2
Q

If released to much, which hormone can cause crushing syndrome?

A

glucocorticoids; cortisol

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3
Q

What are glucocorticoids: cortisol used for?

A

Essential to life, regulates blood sugar, inhibits inflammation, stress response

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4
Q

What can hyperparathyroidism cause

A

constipation, depression, seizures, muscle wasting, polyuria, bone fractures, kidney stones

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5
Q

what can cause hyperparathyroidism

A

adenoma, chronic renal failture, after renal transplant

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6
Q

What can low calcium cause?

A

Irritability, tenancy, seizures

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7
Q

What does parathyroid gland regluate

A

calcium

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8
Q

What are the symptoms of conn’s disease?

A

oedema, hypertension, high sodium, low potassium

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9
Q

What do adrenal glands produce

A

sex hormones ( testosterone, oestrogen) , mineralocorticoids ( aldosterone), glucocorticoids ( cortisol)

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10
Q

What can cause addisons disease ( adrenal insufficiency)

A

autoimmune, infectior, neoplasm

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11
Q

What are the symptoms of crushing syndrome

A

obesity, emotional disturbance, moon face, hypertension, skin uclers

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12
Q

What are the symptoms of addisons disease?

A

Gi symptoms ( anorexia, nausa, vomiting and diarrhoea), weight loss, hperpigmentation, low sodium high potassium

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13
Q

What is the most common type of thyroid cancer

A

papillary carcinoma

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14
Q

What causes hypothyroidism

A

iron deficiency, radioiodine, pituitary defects, autoimmune

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15
Q

What is ishashinoto’s

A

thyroiditis leading to hypothyroidism

cuased by autoimmune destruction of thyroid gland

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16
Q

Symptoms of hypothyroidism?

A

facial and eyelid oedema , extreme fatigue, bradycardia, weight gain

17
Q

How is graves caused

A

auto antibody or TSH receptor, this stimulates hormone synthesis, leading to unregulated

18
Q

What can hyperpituitarism cause

A

adenomas ( a bengin tumour formed of epithelial tissue)

19
Q

What hormones does the posterior pituritary gland in the hypothalamus produce

A

oxytocin and ADH

20
Q

Hypopituitarism related effect

A

injury, surgery, radiation, inflammation

21
Q

What can cause hyperaldosteronism

A

conn’s disease , high renin

22
Q

What are grave’s symptoms?

A

tachycardia, increased systolic bp, breat enlargement, weight loss