Endocrine

Question 1

Decreases Glu absoprtion in gut

Answer 1

alpha-glucosidase inhibitors

Question 2

Rapid acting Insulin

Answer 2

-logs Duration: 3-6hrs often used in conjunction with long lasting insulin

Question 3

DM Dx criteria

Answer 3

Random Glucose >200 w/classic sxs Fasting Glu >126 on 2 occasions A1C >6.5

Question 4

1) Poor HDL 2) BP >135/85 3) TG >150 4) Fasting BS 100-125 5) 24hr OGTT 140-199 6) Central Obesity Predisopses to CAD, CVA, DM

Answer 4

Metabolic syndrome aka Syndrome X aka Insulin resistent Syndrome

Question 5

Short Action Insulin

Answer 5

-alins R (Humalin R and Novalin R) & regular insulin works in 30 mins and lasts 5-8hrs

Question 6

Decreases insulin resistance/ increases insulin sensativity

Answer 6

Thiazolidines (-itazone)

Question 7

Weakness, dry, coarse skin, loss of outer 1/3 of eyebrow, cold intolerance, weight gain, hyporeflexoria, palpable thyroid Increased TSH, decreased T4=essential decreased/norm TSH, decreased free T4=2nd Tx: levothyroxine

Answer 7

Hypothyroidism

Question 8

Decreases hepatic GLU production, increases insulin sensitivity S/e weight loss, GI upset Contra: SrCr >1.5

Answer 8

Metformin

Question 9

Intermediate Insulins

Answer 9

Covers needs for ~12hrs Humalin N Novalin N NPH

Question 10

Graves MC cause Women>men, 20-40yrs. weight loss, anxiety, heat intolerance, warm/moist skin, oncholysis, insomnia, fine tremor, hyperreflexoria, tachycardia, palpitations, exopthalmous Decreased TSH, increased T4, T3 Tx: Thiourea drugs. Propylthiouracil

Answer 10

Hyperthyroidism

Question 11

Stimulates pancreatic production of insulin

Answer 11

Sulfonylureas (-ides)

Question 12

Long Acting (basal) insulin

Answer 12

12-24hrs Glorgin (lantus) can’t be used with other insulins Detemir (levemir) Ultralente