Endocrine Flashcards

1
Q

What is the primary function of insulin in diabetes management?

A

To lower blood glucose levels by facilitating the uptake of glucose into cells.

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2
Q

True or False: Metformin is an insulin secretagogue.

A

False

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3
Q

What class of diabetes medications cause weight gain?

A

Sulfonylureas, thiazolidinediones, insulin.

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4
Q

Fill in the blank: The main risk associated with sulfonylureas is __________.

A

hypoglycemia.

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5
Q

Which diabetes drug classes are known for promoting weight loss?

A

SGLT2 inhibitors and GLP1 agonists.

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6
Q

True or False: DPP-4 inhibitors can cause significant weight gain.

A

False

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7
Q

What hormone do adrenal drugs primarily regulate?

A

Cortisol.

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8
Q

What is the mechanism of action of bisphosphonates in osteoporosis treatment?

A

They inhibit osteoclast-mediated bone resorption.

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9
Q

Which osteoporosis medication needs to be taken for the rest of their life?

A

Denosumab.

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10
Q

True or False: Calcium supplements are sufficient for treating osteoporosis on their own.

A

False

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11
Q

What is a common side effects of corticosteroid therapy?

A

Osteoporosis, cushing syndrome, weight gain, water and sodium retention, infection, hypokalemia.

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12
Q

Fill in the blank: The primary indication for using glucocorticoids is __________.

A

inflammation and immune suppression.

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13
Q

Which diabetes medication class is associated with a risk of bladder cancer?

A

SGLT2 inhibitors.

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14
Q

What is the role of glucagon in diabetes?

A

To raise blood glucose levels by promoting glycogen breakdown.

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15
Q

True or False: Osteoporosis is characterized by increased bone density.

A

False

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16
Q

Which combinations should you avoid for diabetes medication?

A

DPP4 inhibitors with sulfonylureas, GLP 1 agonists or insulin.

17
Q

What is the primary risk factor for developing osteoporosis?

A

Age, particularly postmenopausal women.

18
Q

Which diabetes medication is known for having a low risk of hypoglycemia?

A

Metformin.

19
Q

What is the mechanism of action of thiazolidinediones in diabetes management?

A

They improve insulin sensitivity.

20
Q

True or False: Osteoporosis can be diagnosed with a bone density test.

21
Q

Fill in the blank: The first line treatment of osteoporosis is __________.

A

bisphosphonates.

22
Q

What is the common side effect of SGLT2 inhibitors?

A

Genital yeast infections and UTIs.

23
Q

Which adrenal drug is commonly used to treat Addison’s disease?

A

Hydrocortisone.

24
Q

Fill in the blank: __________ is a condition characterized by excessive cortisol production.

A

Cushing’s syndrome.

25
What is the main benefit of using DPP-4 inhibitors?
They lower blood glucose levels without causing weight gain.
26
True or False: Osteoporosis drugs should only be used in older adults.
False
27
What lifestyle changes can help manage diabetes?
Diet modification, regular exercise, and weight management.
28
Fill in the blank: __________ or _______ are used for type 2 diabetes with cardiovascular and renal disease.
SGLT2 inhibitors, GLP1 agonists.
29
True or False: Insulin can be administered orally.
False
30
What are the two primary types of diabetes?
Type 1 and Type 2 diabetes.
31
Which form of insulin can be given intravenously?
Regular insulin.
32
What is insulin treatment comprised of?
Basal (mandatory long acting) and bolus insulin (meals).