Cardiovascular Flashcards

1
Q

What is the primary mechanism of action of ACE inhibitors?

A

ACE inhibitors block the conversion of angiotensin I to angiotensin II.

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2
Q

True or False: Beta-blockers are contraindicated in patients with asthma.

A

True.

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3
Q

Fill in the blank: Calcium channel blockers primarily cause ____ in the mouth.

A

ginigival hyperplasia

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4
Q

What class of drugs is commonly used as first-line therapy for hypertension?

A

ACE inhibitors and Angiotensin II receptor blockers (ACEIs and ARBs).

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5
Q

Which medication is a direct vasodilator used to treat hypertension?

A

Hydralazine.

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6
Q

What is the primary side effect to watch for with statins and the symptoms?

A

Rahbdomyolysis:
Unexplained muscle and dark coloured urine.

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7
Q

Give examples of anticoagulants and their main counselling points:

A

Factor Xa inhibitors: Apixaban, Rivaroxaban
Direct thrombin inhibitors: Dabigatran
Heparins: Heparin, enoxaparin
Warfarin
Watch for unexplained bruising, dark coloured urine, use an identifying wristband.

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8
Q

Name one common side effect of loop diuretics.

A

Hypokalemia.

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9
Q

Which drug class is known to cause a persistent dry cough as a side effect?

A

ACE inhibitors.

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10
Q

What is the role of nitrates in cardiovascular therapy?

A

Nitrates are used to relieve angina by dilating blood vessels.

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11
Q

Multiple Choice: Which of the following is NOT a beta-blocker? A) Metoprolol B) Atenolol C) Amlodipine D) Propranolol

A

C) Amlodipine.

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12
Q

Fill in the blank: The therapeutic effect of digoxin is primarily related to its ability to increase _____.

A

contractility.

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13
Q

What is the main risk associated with the use of thrombolytics?

A

Bleeding.

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14
Q

True or False: Statins can also have anti-inflammatory effects.

A

True.

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15
Q

What is the wash out period between ACE I and ARBs?

A

36 hours for entresto or 24 hours otherwise.

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16
Q

What is the mechanism of action of aspirin in cardiovascular disease?

A

Aspirin inhibits platelet aggregation.

17
Q

Multiple Choice: Which of the following is a common side effect of calcium channel blockers? A) Bradycardia B) Hypertension C) Hypokalemia D) Hyperglycemia

A

A) Bradycardia.

18
Q

Fill in the blank: The antidote for warfarin is _____.

A

vitamin K.

19
Q

What is the antidote for heparin overdose?

A

Protamine sulfate.

20
Q

True or False: Clopidogrel is an antiplatelet medication.

21
Q

Name one contraindication for the use of beta-blockers.

A

Severe bradycardia.

22
Q

What is the primary purpose of using diuretics in heart failure management?

A

To reduce fluid overload.

23
Q

Multiple Choice: Which medication is used to treat hyperlipidemia? A) Lisinopril B) Simvastatin C) Metoprolol D) Losartan

A

B) Simvastatin.

24
Q

Fill in the blank: The primary action of fibrates is to lower _____ levels.

A

triglyceride.

25
What is the mechanism of action of nitrates?
Nitrates increase nitric oxide, leading to vasodilation.
26
True or False: Patients on factor Xa inhibitors require regular INR monitoring.
False.
27
What is mainstay treatment for heart failure with HFrEF?
1. ACE I or ARB preferrably with an ARNI (sacubitril) 2. Beta-blockers (once euvolaemic) 3. MRA 4. SGLT2 inhibitor
28
Which beta blockers are used for heart failure?
Bisoprolol, metoprolol succinate MR, carvidelol and nebivolol.
29
Which beta blocker also has anti arrhythmic activity?
Sotalol
30
What are the two treatment approaches for af?
Rate or rhythm control.