endocrine

Question 1

symptoms of addisons disease

Answer 1

fatigue
lethargy
anorexia
hyperpigmentation
hypotension
decreased libidoi

Question 2

investigations for addisons

Answer 2

short synachten test
morning serum cortisol
- low Na
- high K+
- high Ca
renin/aldosterone - high renin low aldosterone

Question 3

management of addisons

Answer 3

hydrocortisone
(sick day rules 2x hydrocortisone)

Question 4

most common cause of secondary hypertension

Answer 4

primary hyperaldosteronism

Question 5

investigation of primary hyperaldosteronism

Answer 5

high aldosterone, low renin
saline suppression test
hypokalaemia

Question 6

obesity with proximal myopathy, moon face, frontal balding, buffalo hump, hypertension, bruising on skin

Answer 6

cushing syndrome
(chronic glucocorticoid excess)

Question 7

investigation for cushing syndrome

Answer 7

overnight dexamethasone suppression test
MRI
CT

Question 8

management of cushing syndrome

Answer 8

adrenalectomy
metyrapon
ketoconazole

Question 9

low urine osmolality
high serum osmolality =

Answer 9

diabetes inspidus
(inability to concentrate urine)

Question 10

investigation for diabetes inspidus

Answer 10

water deprivation test
- low urine osmolality