Endocarditis

Question 1

What are the main risk factors for endocarditis

Answer 1

Congenital heart disease or IVDU

Question 2

What are the major criteria for dukes

Answer 2

Two separate blood cultures 30 mins apart with microorganisms typical for infective endocarditis

Echo evidence
New valvular regurgitation

Question 3

What are the minor criteria for dukes

Answer 3

Predisposition 
Temp >38 
Vascular phenomena 
Immunological ohenomena 
Microbio evidence

Question 4

What are the vascular phenomena

Answer 4

Septic emboli Jane way lesions mycotoxins aneurysms conjunctival haemorrhage

Question 5

What are the immunological phenomena

Answer 5

Glomerulonephritis
Older modes
Roth spotsrheumatoid factors

Question 6

What is meant by microbiological evidence

Answer 6

Positive blood culture but not meeting major criteria or serological evidence of active infection with organism consistent with infective endocarditis

Question 7

How many of the major and minor criteria for dukes need to be posting he for endocarditis to be likely

Answer 7

Major. Minor
2 0
1. 3
0. 5

Question 8

Native valve acute organisms and abx

Answer 8

Staph a strep v

Fluclox

Question 9

Native valve subacute

Answer 9

Strep c enterococcus

Ben pen /amoxicillin and gent

Question 10

Prosthetic valve /MRSA

Answer 10

Coat beg staph

Vancomycin gent rifampicin

Question 11

What abx would you give if they have a risk factor for resistance

Answer 11

Vancomycin and meropenem