Antibiotic Man Flashcards

1
Q

what are the indications for IV use?

A

2> outwith normal range (temp, RR, BP, WCC)
febrile with neutropenia or immunocuppression
endocarditis/ septic arthritis/ abcess/ meningitis/ osteoarthritis
oral route compromised
post surgery - unable to tolerate 1l of oral fluids
no oral formulation available

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2
Q

how often should you review IV therapy

A

every 12-24 hours

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3
Q

if IV gent still required after 72 hours consider switch to

A

aztreonam

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4
Q

meningitis

A

ceftriaxone IV and dexamethasone IV

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5
Q

meningitis with suspected encephalitis add

A

acyclovir IV

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6
Q

meningitis if >60yo or immunocompromised

A

add amoxicillin IV

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7
Q

epiglottitis/ supraglottitis

A

ceftriaxone IV

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8
Q

what scoring system is used in CAP

A

CURB65

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9
Q

what is CURB65

A
confusion 
urea >7
RR>20
BP <90/<60
age >65
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10
Q

mild/mod CAP

A

Amoxicillin IV/PO 5 days

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11
Q

mild/mod CAP pen allergy

A

doxy PO or IV clarithromycin if NBM

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12
Q

severe CAP

A

coamoxiclav IV and Doxy PO

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13
Q

severe CAP pen allergy

A

IV levofloxacin

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14
Q

severe CAP in ICU/HDU or NBM

A

IV coamoxiclav and clarithromycin

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15
Q

severe CAP in ICU/HDU or NBM pen allergy

A

IV levofloxacin

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16
Q

any patient with severe CAP should be stepped down to

A

Doxycycline

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17
Q

any patient with severe CAP should be treated for

A

7 days

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18
Q

HAP or aspiration pneumonia severe

A

IV amox met and gent

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19
Q

HAP or aspiration pneumonia severe pen allergy

A

IV cotrimoxazole met +/- gent

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20
Q

all patients with severe HAP should be stepped down to

A

PO cotrimoxazole and metronidazole

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21
Q

patients with severe HAP should be treated for

A

7 days

22
Q

no severe hap

A

PO amox and met

23
Q

non severe hap pen allergy

A

PO cotrimox and met

24
Q

how long should non severe hap be treated for

A

5 days

25
Q

acute exac of copd

A

1- amox

2- doxy

26
Q

acute cough or bronchitis in frail elderly

A

1 - amox

2 - doxy

27
Q

native valve indolent (subacute) endocarditis

A

amox and gent iv

28
Q

native valve severe sepsis acute endocarditis

A

iv fluclox

29
Q

prosthetic valve or suspected mrsa

A

iv vanc and gen with po rifampicin

30
Q

native valve severe sepsis and risk factors for resistant pathogens

A

vanc and meropenem iv

31
Q

non severe c diff

A

po metronidazole 10 days

32
Q

severe c diff

A

vanc po 10 days +/- iv met

33
Q

peritonitis/ biliary tract/ intraabdo

A

iv anox met and gent

34
Q

peritonitis/ biliary tract/ intraabdo step down to

A

PO cotrimox and met

35
Q

peritonitis/ biliary tract/ intraabdo pen allergy

A

IV vanc met and gent

36
Q

proven spontaneous bacterial peritonitis mild

A

Po cotrimoxazole

37
Q

proven spontaneous bacterial peritonitis severe

A

piperacillin/ tazobactam IV

38
Q

proven spontaneous bacterial peritonitis severe step down to

A

co trimoxazole PO

39
Q

uncomplicated lower UTI female

A

nitrofurantoin or trimethoprim 3 days

40
Q

uncathetarised male uti

A

nitrofurantoin or trimethoprim 7 days

41
Q

complicated UTI/ pyelonephritis/ urosepsis

A

IV amox and gent 7 days

42
Q

complicated UTI/ pyelonephritis/ urosepsis pen allergy

A

IV cotrimox and gent 7 days

43
Q

complicated UTI/ pyelonephritis/ urosepsis step down to

A

co trimox

44
Q

cellutitis

A

flucolox 7 days

45
Q

cellulitis pen allergy

A

doxy 7 days

46
Q

acute septic arthritis/ osteomyelitis

A

iv fluclox

47
Q

diabetic foot infection mild

A

fluclox or doxy 7 days

48
Q

diabetic foot infection moderate

A

fluclox + met or
doxy + met
7 days

49
Q

open fracture prophylaxis

A

IV coamoxiclav or (IV cotrimox and met) within 3 hours for max 3 days

50
Q

unknown source

A

IV amox met and gent

consider adding fluclox or vanc if concerned about fluclox

51
Q

unknown source pen allergy

A

IV vanc met and gent