Antibiotic Man Flashcards

1
Q

what are the indications for IV use?

A

2> outwith normal range (temp, RR, BP, WCC)
febrile with neutropenia or immunocuppression
endocarditis/ septic arthritis/ abcess/ meningitis/ osteoarthritis
oral route compromised
post surgery - unable to tolerate 1l of oral fluids
no oral formulation available

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2
Q

how often should you review IV therapy

A

every 12-24 hours

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3
Q

if IV gent still required after 72 hours consider switch to

A

aztreonam

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4
Q

meningitis

A

ceftriaxone IV and dexamethasone IV

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5
Q

meningitis with suspected encephalitis add

A

acyclovir IV

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6
Q

meningitis if >60yo or immunocompromised

A

add amoxicillin IV

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7
Q

epiglottitis/ supraglottitis

A

ceftriaxone IV

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8
Q

what scoring system is used in CAP

A

CURB65

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9
Q

what is CURB65

A
confusion 
urea >7
RR>20
BP <90/<60
age >65
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10
Q

mild/mod CAP

A

Amoxicillin IV/PO 5 days

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11
Q

mild/mod CAP pen allergy

A

doxy PO or IV clarithromycin if NBM

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12
Q

severe CAP

A

coamoxiclav IV and Doxy PO

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13
Q

severe CAP pen allergy

A

IV levofloxacin

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14
Q

severe CAP in ICU/HDU or NBM

A

IV coamoxiclav and clarithromycin

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15
Q

severe CAP in ICU/HDU or NBM pen allergy

A

IV levofloxacin

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16
Q

any patient with severe CAP should be stepped down to

A

Doxycycline

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17
Q

any patient with severe CAP should be treated for

A

7 days

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18
Q

HAP or aspiration pneumonia severe

A

IV amox met and gent

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19
Q

HAP or aspiration pneumonia severe pen allergy

A

IV cotrimoxazole met +/- gent

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20
Q

all patients with severe HAP should be stepped down to

A

PO cotrimoxazole and metronidazole

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21
Q

patients with severe HAP should be treated for

22
Q

no severe hap

A

PO amox and met

23
Q

non severe hap pen allergy

A

PO cotrimox and met

24
Q

how long should non severe hap be treated for

25
acute exac of copd
1- amox | 2- doxy
26
acute cough or bronchitis in frail elderly
1 - amox | 2 - doxy
27
native valve indolent (subacute) endocarditis
amox and gent iv
28
native valve severe sepsis acute endocarditis
iv fluclox
29
prosthetic valve or suspected mrsa
iv vanc and gen with po rifampicin
30
native valve severe sepsis and risk factors for resistant pathogens
vanc and meropenem iv
31
non severe c diff
po metronidazole 10 days
32
severe c diff
vanc po 10 days +/- iv met
33
peritonitis/ biliary tract/ intraabdo
iv anox met and gent
34
peritonitis/ biliary tract/ intraabdo step down to
PO cotrimox and met
35
peritonitis/ biliary tract/ intraabdo pen allergy
IV vanc met and gent
36
proven spontaneous bacterial peritonitis mild
Po cotrimoxazole
37
proven spontaneous bacterial peritonitis severe
piperacillin/ tazobactam IV
38
proven spontaneous bacterial peritonitis severe step down to
co trimoxazole PO
39
uncomplicated lower UTI female
nitrofurantoin or trimethoprim 3 days
40
uncathetarised male uti
nitrofurantoin or trimethoprim 7 days
41
complicated UTI/ pyelonephritis/ urosepsis
IV amox and gent 7 days
42
complicated UTI/ pyelonephritis/ urosepsis pen allergy
IV cotrimox and gent 7 days
43
complicated UTI/ pyelonephritis/ urosepsis step down to
co trimox
44
cellutitis
flucolox 7 days
45
cellulitis pen allergy
doxy 7 days
46
acute septic arthritis/ osteomyelitis
iv fluclox
47
diabetic foot infection mild
fluclox or doxy 7 days
48
diabetic foot infection moderate
fluclox + met or doxy + met 7 days
49
open fracture prophylaxis
IV coamoxiclav or (IV cotrimox and met) within 3 hours for max 3 days
50
unknown source
IV amox met and gent | consider adding fluclox or vanc if concerned about fluclox
51
unknown source pen allergy
IV vanc met and gent