Endo, Immuno

Question 1

reliable index of long-term glycemic control

Answer 1

Glycosylated Hgb

Question 2

represents the fraction of Hgb to which glucose has been nonenzymatically attached in the bloodstream

Answer 2

Glycohemoglobin (HbA1c)

Question 3

This deficiency leads to recurrent RUG INFECTION (Respi-urogenital-GI)

Answer 3

Vitamin A deficiency

Question 4

B cell Immunodeficiency Disorder (few or absent B cells)

Answer 4

Bruton disease X liked agammaglobulinemia

healthy infants unitl 6mos – recurrent infections

Question 5

Gold standard in the diagnosis of food allergy

Answer 5

double blind Placebo Controlled Food Challenge

Question 6

Become symptomatic during the 1st or 2nd year of life with recurrent pyogenic infections;
neutropenic;
P. jiroveci pneumonia

Answer 6

Hyper IgM syndrome

Failure to produce IgG, IgA, IgE antibodies with normal or ↑ IgM

Question 7

present w/in the 1st few months of life with recurrent or persistent diarrhea, pneumonia, OM, sepsis, skin infections;
persistent infections with opportunistic agents;
unable to reject foreign tissue

Answer 7

SCID - most severe immunodeficiency

Absence of T- and Bcell functions

Question 8

Immunodeficiency with thrombo-cytopenia and eczema;
prolonged bleeding from circumcision site or bloody diarrhea during infancy

Answer 8

Wiskott-Aldrich syndrome
T cell deficiency

Question 9

Degranulation abnormality
disordered coalescence of lysosomal granules

Answer 9

Chediak-Higashi syndrome - AR

Recurrent pyogenic infections
neutropenia;
hepatosplenomegaly
light skin and silvery hair; photophobia

Question 10

Neutrophilia;
recurrent bacterial infection associated with a lack of pus formation;
bleeding tendency; delayed umbilical cord separation with significant omphalitis;

Answer 10

Leukocyte adhesion deficiency (1-3) AR

Adhesion abnormality
decreased binding of C3b to neutrophils