Emotion and Motivation Flashcards
behaviour is influenced by…..
internal states
basic internal states =
4 F's feeding fighting fleeing mating
all homeostatic systems have the same basic structure
perturbation knocks off controlled variable
sensor compares variable to a set point
if theres a difference, it will send an error signal to an effector to counteract the perturbation
orexigenic
hunger
anorexigenic
not hunger
‘satiety’
lateral hypothalamus
‘excites’ eating
if areas removed - animal never ate
contains neurons that use specific neuropeptides to transmit info
orexin and MCH
ventromedial nucleus
satiety area
stimulation leads to inhibtion of eating
remove area = animal never stopped eating
mechanisms for regulating hunger
hypothalamus
long term
lateral hypothalamus
ventromedial nucleus
leptin
hormone produced by fat that reduces fat
mutant mouse - obese - ob/ob
ob/ob mice lacked leptin
but if linked ob/ob mouses bloodstream to wt mouse - it loses weight — how they found out it was a hormone
ways of leptin reducing body fat (2)
1 - inhbit eating
2 - increase metabolic rate = inhibits production of body fat
leptin inhibiting eating …..
pathway passes through arcuate nucleus
contains 2 populations of neurons that use 2 distinct peptides:
1 - produces POMC/aMSH/CART –> inhibits lateral hypo = stops excitation of eating
2 - inhibits production of NPY/AgRP (connects to lateral hypo and normally triggers eating but is inhibited)
both connect to paraventriular nucleus but work oppositely so…
POMC excites nucleus which inhibits eating vs NPY inhibits nucleus
leptin on metabolic rate
neurons in arcuate nucleus connect to para/symp
POMC excited symp NS = inc metabolic rate
NPY excited para NS = inhibits inc in metabolic rate
paraventricular nucleus excites TSH which inc metabolic rate
blood glucose on regulating hunger
short term
inhibits lateral hypo = normally excites eating but is inhibited
excites ventromedial nucleus = inhibits eating
insulin
- excites POMC
- inhibits NPY
fear
amygdala - activated when veiwing fearful faces
lesions in amygdala - animals showed less fear
agression
cerebral cortex —-> amygdala —– > signals to hypothalamus —–> PAG, ventral tegmental area = aggressive behaviour