Emergomycosis Flashcards
Under which genus was emergomycosis initially classified?
Emmania genus
What are the 5 species of emergomycoses?
E. pasteurianus
E. africanus
E. canadensis
E. orientalis
E. europaneus
What is the reservoir of emergomycosis?
Soil therefore risk associated with airborne conidia from soil/dust exposure
What is the clinical presentation of emergomycosis?
Primary - unknown
Secondary
- skin
- lung
- RES
How is emergomycosis diagnosed
Culture (can take up to 6w)
Microscopy (yeasts)
Cross reacts with commercial histoplasma antigen kit
What is the treatment of all non-mild fungal disease?
Amphotericin B 10-14d then itraconazole
What is the treatment of all emergomycosis?
Amphotericin B
What is the treatment of all talaromycosis?
Amphotericin B
What is the duration of anti fungal treatment in histoplasmosis?
6-12m
What is the duration of anti fungal treatment in blastomycosis?
6-12m
What is the duration of anti fungal treatment in coccidiodomycosis?
Acute pulmonary: 3-6m
Chronic pulmonary: longer
CNS, SOT, HSCT - lifelong
What is the duration of anti fungal treatment in paracoccidiodomycosis?
9-12m
What is the duration of anti fungal treatment in emergomycosis?
9-12m
What is the duration of anti fungal treatment in talaromycosis?
9-12m
In which patients must coccidioidomycosis be treated?
- Immunosuppressed
- Underlying cardiopulmonary disease
- CF titres>1:32
- > 10% weight loss
- > 50% lung infiltrated