Emergency Medicine Flashcards
what risk factors are there for neonates for sepsis?
prematurity
prolonged rupture of membranes
maternal intrapartum pyrexia
maternal colonisation of group B strept
what are some risk factors of sepsis in children?
immunocompromised - chemo, drugs for autoimmune disorders
history of fever
Non-specific symptoms such as lethargy, nausea and vomiting, headache and abdominal pain also occur commonly.
what are some signs of sepsis ?
hypotension, tachycardia, cool peripheries, confusion
Signs of the source of infection, such as crackles on chest auscultation or an area of cellulitic skin
non-blanching rash is suggestive of meningococcal disease
what are some DD of sepsis ?
uncomplicated infection leukaemia aplastic anaemia malignancy autoimmune disorder (JIA) Kawasaki disease
what lab tests should be done for sepsis ?
blood gas FBC CRP blood culture urinanalysis stool culture
CXR
Abdo US
LP
what should lab testing be done on an under 5 yr?
if there are any red features present
state some red features ?
pale mottled blue skin no response to social cues weak high pitched cry grunting tachypnoea chest indrawing reduced skin turgor non blanching rash bulging fontanelles neck stiffness focal near signs
what are children prone to during sepsis/infection?
hypoglycaemia
how should hypoglycaemia be treated in children?
2ml/kg bolus of 10% dextrose if blood sugar is <3mmol/L.
during sepsis what would th blood gas results show?
metabolic acidosis
what are 3 characteristics of DKA?
acidosis pH <7.3 or HCO3 <18
ketonaemia blood ketones >3
hyperglycaemia >11mmol/l
what is the chemical name of ketones ?
beta-hydroxybutyrate
what three complications can occur with DKA?
cerebral oedema, hypokalaemia and aspiration pneumonia.
what is the mortality for cerebral oedema?
25%
what breaks down to form ketones?
adipose tissue
what are some risk factors for DKA in children?
Non-compliance with insulin treatment or a high sugar diet
Intercurrent illness, especially infection
Rapidly changing insulin requirements during puberty
Failure of insulin pump