Emergency flashcards herpes virus antivirals
1
Q
What two major points differentiate Gancyclovir (and valgancyclovir) from acyclovir?
What is Ganciclovir the drug of choice for?
What are two toxicities of Ganciclovir?
A
2
Q
Which two enzymes are altered in order to provide restistance to ganciclovir?
A
3
Q
What is the MoA of foscarnet?
Does it require phosphorylation to become active?
What are three major toxicities?
A
4
Q
What characterizes cidofovir?
Does it require phosphorlyation to become active?
What are its major toxicities?
A
5
Q
What is the MoA of letermovir?
Against what herpesvirsus is it used?
What toxicities does it have?
A
6
Q
hWhat is the MoA of maribavir?
With what other drug should it not be given?
What toxicity does it have?
For what virus is it used?
A
