Embryonic Disk and more Flashcards

1
Q

label the parts of the embryonic disk

A

drawn out

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2
Q

what is the amniotic cavity

A

forms the inside inner cell mass and surrounded by layer of cells called the amnion or amniotic sac

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3
Q

what structures form after implantation

A

embryonic disk
composed of 2 layers - epiblast and hypoblast
- the amniotic cavity eventually covers the developing embryo providing a protective fluid bag

yolk sac
forms inside blastocele from hypoblast

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4
Q

what is the epiblast

A

its 3 germ layers that becomes the embryo

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5
Q

what is the hypoblast

A

its extraembryonic memebrane and helps with extra embryonic tissue

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6
Q

explain what happens during day 13-14 (gastrulation) - formation of germ layers

A
  • cephalic end = Becomes head
  • caudal end = Becomes base of torso
  • epiblast layer multiplies and thickens along primitive streak

These 3 germ layers are gonna form all of the body tissues:
- Ectoderm –> skin and most of nervous system
- Mesoderm –> blood supply, bones and muscles
- Endoderm –> digestive system, lungs

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7
Q

describe the formation of the germ layers

A

endoderm
- Inner layer
- forms lining of digestive tract and derivatives

mesoderm:
- middle layer
- forms tissues like muscle, bone. blood vessels

ectoderm:
- outer layer
- forms skin and nervous system

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8
Q

what happens at day 16 - formation of notochord

A
  • mesodermal cells are formed
  • solid cylinder of cells under the ectoderm –> becomes neural plate at day 18
  • notochord is involved in induction of signals from ectoderm to the neural plate and it at the cephalic end (the primitive streak is at caudal end)
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9
Q

what does the oropharngeal membrane becomes?

A

mouth

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10
Q

what does the cloacal membrane becomes?

A

anus - end of digestive system

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11
Q

what happens on day 18-26 - formation of neural tube

A
  • Notochord has sent a signal to ectoderm –> thickens it and becomes neural plate
    neural plate Forms neural folds and a central indentation called a neural groove
    -
    Neural folds becomes higher and neural indentations get bigger
  • Ridges = crest of neural fold
  • Crests come together and form an outer layer (becomes skin) at the top and it makes a tube in the middle (neural tube that becomes spinal cord and brain)
  • Outside neural tube theres somites thats formed from mesoderm
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12
Q

what does the neural tube form

A

forms the brain and spinal cord (CNS)

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13
Q

what does the neural crest form?

A
  • sensory and post ganglionic autonomic (cant consciously control) portions of PNS
  • general CT of the head
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14
Q

what is a somite formed from and what does it become?

A

formed from mesoderm adjacent to neural tube

eventually become vertebral column, ribs, and some skeletal muscle

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15
Q

what is the importance of the neural plate and how is it formed?

A

it becomes the spinal cord and brain

the notochord sends signals from the mesoderm to the ectoderm layer to thicken ectoderm and become neural plate

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16
Q

what are the two types of embryonic folds? explain.

A
  1. lateral body fold
    - across the length of the neural tube
  2. fold in the median plane
    - this forms the ends called the hindgut and foregut
17
Q

what does the lateral fold produce?

A
  • it forms the gut tube from the endoderm
  • coelom within the mesoderm –> body cavities
  • ectoderm –> skin
18
Q

what does the median plane fold produce?

A
  • foregut and hindgut
  • allantois
19
Q

What is the allantois?

A

a region of the yolk sac that is pinched off and ends up in the connecting stalk and becomes a part of the urinary system.

20
Q

what happens at day 20 of embryo folding and gut formation?

A

the amniotic cavity folds around the 3 germ layers into 2 different ways

  • longitudinally - forms gut tube
  • medially - forms head and tail
21
Q

what happens at day 25 of embryo folding and gut formation?

A
  • the folds get closer to each other and the midgut is now defined.
  • oropharyngeal is in contact with endoderm = mouth opening
  • cloacal membrane and region under disappear = anus
  • yolk sac is narrowed and celom gets longer
22
Q

what happens at day 30 of embryo folding and gut formation?

A

lateral folds fuse to form:
- amniotic cavity is around all germ layers like the whole embryo
- gut tube from oropharyngeal to cloacal membrane

evaginations from gut tube form:
- anterior pituitary, thyroid gland, lungs, liver, pancreas
- branchial arches

coelom:
- fuses around the heart as pericardial cavity
- expands to become the pleural and peritoneal cavities
- cavities become separate entities.

23
Q

what is evagnation

A

turning the gut tube inside out?

24
Q

what is the coelom?

A

A fluid-filled cavity lined by mesoderm tissue.

25
Q

what do brachial arches form?

A

pharynx, auditory tubes, tonsils, thymus and parathyroid glands

26
Q

when does limb bud development occur?

A

upper limb = day 24
lower limb = day 28

27
Q

what is limb bud development?

A
  • limbs grow from proximal to distal
  • mesoderm cells are proliferating
28
Q

what is the apical ectodermal ridge?

A

thickened ectoderm at distal end of each developing limb that stimulates outward growth

29
Q

what is the protein for limb bud development called?

A

sonic hedgehog

30
Q

what did taking thalidomide cause problems in children?

A

def: thalidomide = drug given to prego women to reduce sickness

caused:
because it inhibits the formation of blood vessels. if the apical ectodermal ridge doesnt have enough blood supply to grow it wont and the limb will be stunted

31
Q

where is the skeleton derived from?

A

mesoderm or neural crest cells

32
Q

where are muscles derived from?

A

myoblasts - derived from the somites that develop into skeletal muscle fibers

33
Q

where is the nervous system derived from?

A

neural tube and neural crest cells

34
Q

what is the foregut

A

oral cavity

35
Q

what is the hindgut

A

anus

36
Q

what is the midgut

A

mid duodenum