embryology vasculature Flashcards

1
Q

timeframe of vessel formation

A

week 3- birth

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2
Q

diffusion time period

A

first 2 weeks: zygotic period

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3
Q

vitelline time period

A

week 3-8 (emb period)

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4
Q

when does heart beat

A

day 21

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5
Q

Placental stage period

A

week 9-birth (fetal period)
after yolk contents are depleted

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6
Q

how many arteries and veins in umbilical cord

A

2 arteries and 1 vein

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7
Q

what is the purpose of the vitelline vessels

A

bring nutrients from yolk cavity to the interior of the embryo
- also skin is forming and preventing diffusion of oxygen

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8
Q

when is the neonatal circulation stage

A

at birth when systemic and pulmonary circuits become distinct

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9
Q

what do hemangioblasts form

A

primitive erythrocytes and endothelial precursor cells
- hemangiogenesis is coulpled to hematopoesis

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10
Q

what is the main hematopoietic organ of embryo and fetus

A

the liver
by day 60 switch from yolk sac and liver occurs

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11
Q

outside the embryo and yolk sac derivative

A

extra embryonic mesoderm

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12
Q

inside the embryo and yolk sac derivative

A

intraembryonic mesoderm

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13
Q

hemangiogenesis coupled to hematopoiesis where

A

outside embryo

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14
Q

hemangiogenesis not coupled to hematopoiesis where

A

inside the embryo

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15
Q

hemangioblasts are where

A

outside embryo, none inside

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16
Q

vasculogenesis

A

formation of vessels from scratch: occurs in the yolk sac

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17
Q

angiogenesis

A

formation of vessels from existing vessels

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18
Q

how does sprouting angiogenesis work

A

part of vessels stalk off

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19
Q

how does intussusception angiogenesis occur

A

1 vessel splits into 2 vessels

20
Q

major artery running through embryo

A

dorsal aorta

21
Q

branches off dorsal aorta

A

dorsal segmental arteries
ventral sengmental arteries
lateral segmental arteries

22
Q

how many aortic arches

23
Q

aortic sac becomes what

A

heart tube

24
Q

aortic sac is connected to the arches via

A

right and left dorsal aortas

25
aberrant right subclavian artery
part of right dorsal aorta fails to regret and the 4th arch artery regresses causing right subclavian to be a branch off aorta behind the esophagus
26
issues with aberrant right subclavian artery
esophagus can press on right subclavian and cause BP drop in right sided UE pressure right subclavian can also press on esophagus to cause dysphagia
27
association with aberrant right subclavian artery
down sydrome
28
double aortic arch
failure of regression of right dorsal arch causing a vascular ring around trachea and esophagus causing dysphagia or dyspnea
29
double aortic arch association
Digeorge syndrome: 20% have double aortic arch
30
right sided aortic arch
left regresses and right is retained - only an issue if the ligament arteriousus is running behind esophagus and trachea
31
right sided aortic arch is associated with
tetralogy of fallot
32
interrupted aortic arch
differential cyanosis due to LE supplied by pulmonary trunk via patent ductus aretriousus
33
interrupted aortic arch association
digeorge syndrome
34
coarction- post ductal
lower extremities don't receive enough oxygenated blood collateral vessels form which bypass the coarction to prevent issues asymptomatic
35
coarction- pre ductal
LE do not receive enough oxygenated blood after ductus arteriousus closes, differential cyanosis commonly occurs
36
pre ductal coarction association
Turner syndrome patients
37
Vitelline veins
hooked up to sinus venosus, running through liver rudiment
38
what happens to cranial part of left vitelline vein
it regresses, shunting blood to right side of heart
39
what happens to the caudal part of left vitalize vein
regresses to form just 1 vitelline vein on the right side
40
what things form from the right vitteline vein
portal vein splenic vein inferior mesenteric vein
41
what do the umbilical veins carry
oxygenated blood
42
which umbilical vein regresses
right
43
what happens to cranial left umbilical vein
regresses
44
umbilical vein track
directly to ductus bypassing liver
45
umbilical vein becomes what in adult
ligamentum teres hepatis
46
ductus venosus becomes what in adult
ligamentum venosum