Embryology of the GI Tract/Stomach Flashcards
What are the three independent parts of the alimentary tract in early embryological development?
Foregut, midgut, hindgut
The foregut forms what structures?
Distal esophagus, stomach, and part of the duodenum
Where does the foregut end?
Second part of the duodenum at the entrance of the bile duct
Where does the midgut begin and end?
Begins are the entrance of the bile duct into the second part of the duodenum and ends with the right 2/3 of the transverse colon
Where does the hindgut begin and end?
Begins with the left 1/3 of the transverse colon and ends in the upper part of the anal canal
Why are the three embryological divisions of the GI tract important?
The adult derivatives of each have a unified blood supply and autonomic nerve supply
All of the blood supply to the foregut, midgut, and hindgut come from what place?
Abdominal aorta
What is the blood supply to the foregut?
Branches of the celiac trunk
What is the blood supply to the midgut?
Branches of the superior mesenteric artery
What is the blood supply to the hindgut?
Branches of the inferior mesenteric artery
What is the sympathetic innervation of both the foregut and midgut?
Greater splanchnic nerves (T5-T9) and lesser splanchnic nerves (T10-T11)
What is the sympathetic innervation of the hindgut?
Lumbar splanchnic nerves (L1-L2)
What is the parasympathetic innervation of both the foregut and midgut?
Vagus nerve
What is the parasympathetic innervation of the hindgut?
Pelvic splanchnic nerves (S2-S4)
What is the sympathetic effect on the GI tract?
Decreased motility and tone and contraction of sphincters
What is the parasympathetic effect on the GI tract?
Increased motility and tone and relaxation of sphincters
What are the four major layers of the gut wall?
Mucosa, submucosa, muscularis externa, serosa/adventitia
What layer of the gut wall is a mucous membrane (important for absorption) that contains the muscular mucosae with is a thin layer of smooth muscle?
Mucosa
Which layer of the gut wall is very vascular?
Submucosa
Which layer of the gut wall is a loose connective tissue layer containing blood vessels and lymphatics?
Submucosa
What layer of the gut wall is a thick layer of smooth muscle responsible for peristalsis?
Muscularis externa
Peristalsis moves in which direction?
Distally
The muscularis external consists of what two layers?
Inner circular layer and outer longitudinal layer
What is another name for visceral peritoneum of the gut wall?
Serosa
What is the name for the connective tissue coat covering retroperitoneal organs?
Adventitia
What is the name of the semi-independent regional system of nerves responsible for the gut?
Enteric nervous system
Where is the submucosal plexus located?
Within the submucosa near its border with the muscularis externa
What do the postganglionic fibers of the submucosal plexus supply?
Muscularis mucosae and mucus secreting glands
Where is the myenteric plexus located?
Between the circular and longitudinal layers of muscularis externa
What do the postganglionic fibers of the myenteric plexus supply?
Both layers of the muscularis externa
What action is the myenteric plexus responsible for?
Stimulation of peristalsis
What is the shape of the stomach when empty?
J-shaped
What is the capacity of the stomach?
2-3 liters
What are examples of foreign things the stomach can absorb?
Some drugs and alcohol
The stomach lies in what regions of the abdomen?
Left hypochondriac, epigastric, and umbilical regions