Embryology- GI/Pelvis/Perineum Flashcards
What is the original structure that forms the GI tract?
Yolk sac
What do the umbilical arteries become in adults?
Medial umbilical ligaments
What does the urachus become in adults?
Median umbilical ligament
What is the urachus?
Fetal structure that drains urine from fetus to the amnionic sac
- It is the distal portion of allantois that forms later on, remains as median umbilical fold in adults
What does the umbilical vein become in adults?
Falciform ligament and round ligament of the liver (left UV)
What is the allantois?
- Vestigal structure in humans, serves as waste storage until bladder forms
- In birds and lower reptiles, it serves as a respiratory/ waste storage structure
Can cause pathologies in humans if it stays open
What is Meckel’s diverticulum?
- Remnant of vitelline duct in some people, presents as outpouching of intestine
can be connected with fibrous cord to umbilicus (from small intestine)
What does the vitelline vein become in adults?
Portal vein
What do the vitelline arteries become in adults? What areas do they supply?
- Celiac trunk (supplies foregut)
- Superior mesenteric artery (supplies midgut)
- Inferior mesenteric artery (supplies hindgut)
What structures are in the umbilical cord?
- Umbilical arteries
- Umbilical veins
- Vitelline arteries
- Vitelline veins
- Vitelline duct
- Allantois/urachus
- STEM CELLS
What are caval veins (specific to GI)?
Veins that take waste products from intestines to Inferior Vena Cava
What is the stomodeum?
(Primitive) oral cavity
- Ectoderm lined with endoderm
What is the proctodeum?
Tubes within the cloaca that later form:
- Anus
- Vagina (when female)
- Urethra
How does the GI tract rotate?
Note: starts around 50 days
- Intestines herniate into umbilical cord (maybe because there is more space there)
- Intestines loops 180 degrees (or so) around the superior mesenteric artery
- As it grows, the arteries stretch also
- Parietal peritoneum stretches over duct and arteries as they change in conformation to become the viseral peritoneum
- As organs stretch into peritoneum, mesentaries form, which do not separate during intestinal looping - Final positioning is ascending, transverse, and descending colon surrounding small intestine
- Intestines then fall back in to abdomen once folded
What is a retroperitoneal organ?
- Immovable and fixed organ, does not have a mesentary
What is an intraperitoneal organ?
- Movable organ, has a mesentary
What structures are in the foregut?
- Esophagus
- Stomach
- Liver
- Gallbladder
- Pancreas
- Spleen
- First half of duodenum (and part of second half per Dr. Solunias)
Supplied by Celiac trunk
What structures are in the midgut?
- Last 1/4-1/2 of duodenum
- Jejunum and Ileum
- Caecum
- Appendix
- Ascending colon
- Proximal 2/3 transverse colon
Supplied by Superior mesenteric artery
What structures are in the hindgut?
- Distal transverse colon (left 1/3)
- Descending colon
- Sigmoid colon
- Rectum
Supplied by inferior mesenteric artery
How do the liver and its blood supply form?
- Liver cells differentiate and migrate underneath heart (part of yolk sac/gut)
- Vitelline vein runs through early heart and liver
- Liver also forms complex network of veins, anastomoses between umbilical veins and vitelline veins
What is the early gallblader-liver connection?
The liver and gall bladder forms a fibrous matrix of the septum transversum and endodermal diverticula from gut
- Veins invade within
How does the pancreas form?
- Dorsal pancreas forms across from gallbladder on gut
- Ventral pancreas forms on opposite side next to gallbladder
- Ventral pancreas then flips and rotates to same side as dorsal pancreas
- Ventral and dorsal pancreases then join together, still retain two separate ducts (that connect at one point)
Accessory pancreatic duct is on original dorsal pancreas
Pancreatic duct is on original ventral pancreas