Embryology derivatives Flashcards

1
Q

Lens of eye

A

Surface ectoderm

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2
Q

Spleen

A

Mesoderm (derived from foregut mesentary)

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3
Q

Eustachian tube

A

endoderm (luminal epithelial derivative)

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4
Q

Muscle, bone, CT

A

Mesoderm

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5
Q

Gut tube epithelium (including anal canal above the pectinate line)

A

Endoderm

eg esophagus

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6
Q

Lymphatics

A

Mesoderm

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7
Q

3 types of ectoderm

A

neural crest
neuroectoderm
surface ectoderm

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8
Q

Brain (CNS neurons, neurohypophysis, oligodendrocytes, astrocytes, pineal gland)

A

neuroectoderm

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9
Q

PNS (DRG, CN, autonomic ganglia, Schwann cells)

A

Neural crest

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10
Q

Kidneys

A

mesoderm

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11
Q

ovaries, testes

A

mesoderm

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12
Q

dermis

A

mesoderm

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13
Q

pancreas

A

endoderm

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14
Q

gallbladder, liver, lungs

A

endoderm

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15
Q

what structure induces ectoderm to form neuroectoderm (neural plate)

A

notochord

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16
Q

blood

A

mesoderm

17
Q

cardiovascular structures

A

mesoderm

18
Q

most of urethra and lower vagina

A

endoderm

19
Q

upper vagina

A

mesoderm

20
Q

Thyroid, parathyroid, thyroid follicular cells

A

endoderm (luminal epithelial derivatives)

21
Q

serous linings of body cavities (eg peritoneum)

A

mesoderm

22
Q

chromaffin cells of adrenal medulla

A

neural crest

23
Q

parafollicular cells of thyroid

A

neural crest

24
Q

sweat, mammary glands

A

surface ectoderm

25
Q

melanocytes

A

neural crest

26
Q

adenohypophysis

A

surface ectoderm

27
Q

retina

A

neuroectoderm

28
Q

Hirschsprung disease is due to a defect in what embryonic tissue?

A

neural crest (forms ganglionic plexus)
Always affects rectum and anus (neural crest cells migrate caudally)
75% of the time affects sigmoid colon

29
Q

Above pectinate

A

endoderm

30
Q

below pectinate

A

ectoderm

31
Q

difference between multipotent and totipotent stem cells?

A

Totipotent - derived from more primitive cells than multipotent. Zygote is totipotent during normal differentiation. Can develop into all the various cell types. Once in the 3 basic tissue types (mesoderm, ectoderm, and endoderm), the tissues are multipotent.

32
Q

What structure in the female develop from the same structures that failed to dev in hypospadia?

A

Male - urethral folds

female - labia minor

33
Q

Crura of the clitoris in females is equivalent to what in the male?

A

Crura of penis

Both developed from genital tubercle

34
Q

Labia majora in females is equivalent to what in the male?

A

scrotum

35
Q

Round ligament and ovarian ligaments are adult remnants of the caudal genital ligaments. These are equivalent to what in the male?

A

Caudal portions of the gubernaculum testis

36
Q

Craniopharyngiomas are derived from what? What else forms from this?

A

Rathke’s pouch - oral ectoderm (diverticulum of the roof of the embryonic oral cavity)
Anterior pituitary arises from this as well

37
Q

What forms the aorticopulmonary septum and endocardial cushions.

A

Ectodermal Neural crest cells

38
Q

Microglia (like Macrophages)

A

Mesoderm