Embryology derivatives Flashcards
Lens of eye
Surface ectoderm
Spleen
Mesoderm (derived from foregut mesentary)
Eustachian tube
endoderm (luminal epithelial derivative)
Muscle, bone, CT
Mesoderm
Gut tube epithelium (including anal canal above the pectinate line)
Endoderm
eg esophagus
Lymphatics
Mesoderm
3 types of ectoderm
neural crest
neuroectoderm
surface ectoderm
Brain (CNS neurons, neurohypophysis, oligodendrocytes, astrocytes, pineal gland)
neuroectoderm
PNS (DRG, CN, autonomic ganglia, Schwann cells)
Neural crest
Kidneys
mesoderm
ovaries, testes
mesoderm
dermis
mesoderm
pancreas
endoderm
gallbladder, liver, lungs
endoderm
what structure induces ectoderm to form neuroectoderm (neural plate)
notochord
blood
mesoderm
cardiovascular structures
mesoderm
most of urethra and lower vagina
endoderm
upper vagina
mesoderm
Thyroid, parathyroid, thyroid follicular cells
endoderm (luminal epithelial derivatives)
serous linings of body cavities (eg peritoneum)
mesoderm
chromaffin cells of adrenal medulla
neural crest
parafollicular cells of thyroid
neural crest
sweat, mammary glands
surface ectoderm
melanocytes
neural crest
adenohypophysis
surface ectoderm
retina
neuroectoderm
Hirschsprung disease is due to a defect in what embryonic tissue?
neural crest (forms ganglionic plexus)
Always affects rectum and anus (neural crest cells migrate caudally)
75% of the time affects sigmoid colon
Above pectinate
endoderm
below pectinate
ectoderm
difference between multipotent and totipotent stem cells?
Totipotent - derived from more primitive cells than multipotent. Zygote is totipotent during normal differentiation. Can develop into all the various cell types. Once in the 3 basic tissue types (mesoderm, ectoderm, and endoderm), the tissues are multipotent.
What structure in the female develop from the same structures that failed to dev in hypospadia?
Male - urethral folds
female - labia minor
Crura of the clitoris in females is equivalent to what in the male?
Crura of penis
Both developed from genital tubercle
Labia majora in females is equivalent to what in the male?
scrotum
Round ligament and ovarian ligaments are adult remnants of the caudal genital ligaments. These are equivalent to what in the male?
Caudal portions of the gubernaculum testis
Craniopharyngiomas are derived from what? What else forms from this?
Rathke’s pouch - oral ectoderm (diverticulum of the roof of the embryonic oral cavity)
Anterior pituitary arises from this as well
What forms the aorticopulmonary septum and endocardial cushions.
Ectodermal Neural crest cells
Microglia (like Macrophages)
Mesoderm