Embryology and Anatomy of Kidney & Ureters Flashcards
Urogenital system develops from which germ layer
Intermediate mesoderm
excretory duct of the urinary and genital system opens into this common cavity
Cloaca
Components of the nephrogenic cord
pronephros
mesonephros
metanephros
Mesonephric (Wolffian) duct persists in males as
epididymis, ductus deference & ejaculatory duct
Component of the nephrogenic cord that will form the adult kidney
Metanephros
The first embryological derivative of the adult kidney is formed during which week
5th week
The mesonephric duct forms which part of the adult kidney
Collecting part
The metanephric duct forms which part of the adult kidney
Excretory part
The ureteric bud come from which embryological derivative
mesonephric duct
Which structure of the nephron is the first that comes form the ureteric bud
Collecting duct
Fetal kidneys become functional at which ____ week
12th
Wilms tumor
- affects which population?
- mutation of which gene?
- Children under 5yrs
- mutation in WT 1
Polycystic kidney
- presentation?
- basis for absence of collecting ducts
- Numerous ducts are surrounded by undifferentiated cells
- Nephrons fail to develop
- Ureteric bud fail to branch hence collecting ducts never form
Renal agenesis
- two causes?
- mutation in which gene?
Due to failure of ureteric bud to develop
OR
Due to interaction between metanephric mesoderm & ureteric bud fails to occur
- Mutation of GDNF gene
Potters sequence
- what is it?
- reason for anuria and oligohydramnios
Bilateral renal agenesis
- Anuria because of the lack of kidneys, urine cannot be made
- Oligohydramnios because a lack of kidneys prevents recycling of amniotic fluid so amniotic fluid becomes low.
Two types of Duplication of ureters
Partial and incomplete
Final vertebral location of kidneys in adults
T12 to L3
Arterial supply of kidneys while in pelvis fetally
Pelvis branches of aorta
Pelvic kidney
- cause?
Failure of ascent from pelvic position to abdomen
Horseshoe kidney
- presentation?
- cause?
- Inferior poles of both kidneys fuse
- The ascent of horseshoe kidney is prevented by the root of inferior mesenteric artery
Urorectal septum forms during ____ week
7th
Urorectal septum
-what it the function?
separate the urogenital sinus from the anal canal