Embryology Flashcards

1
Q

From what does the urogenital tract develop?

A

Intermediate mesoderm

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2
Q

From when does sexual differentiation occur?

A

7 weeks on

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3
Q

What triggers development of the male genital tract?

A

Sex determining region of Y (SRY) transcription factor

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4
Q

What do the somatic support cells differentiate into in males?

A

Sertoli cells

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5
Q

What does the male genital tract develop from?

A

Mesonephric (Wolffian) duct

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6
Q

What do sertoli cells produce?

A

Anti-Mullerian hormone

Stim production of Leydig cells

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7
Q

What do Leydig cells produce?

A

Testosterone

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8
Q

What does testosterone induce?

A

Formation of epididymis, vas deferens, seminal vesicles

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9
Q

What does Dihydrotestosterone (DHT) induce?

A

Male specific external genitalia

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10
Q

What does Persistent Mullerian Duct Syndrome produce?

A

Uterus, vagina and uterine tubes
Testes in ovarian location
Male external genitalia

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11
Q

What is an undescended testes called?

A

Cryptorchidism

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12
Q

When do male accessory glands develop?

A

10w

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13
Q

What are the three accessory glands in males?

A

Bulbourethral and prostate

Seminal vesicle

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14
Q

What stimulates the development of the female genital tract?

A

Absence of SRY transcription factor

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15
Q

What do somatic support cells differentiate into in females?

A

Granulosa cells

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16
Q

What do germ cells differentiate into in females?

A

Oocytes

17
Q

What is a combination of an oocyte and granulosa cells called?

A

Primordial follicles

18
Q

What ducts do the female genital tract develop from?

A

Paramesonephric (Mullerian) ducts

19
Q

What do the Paramesonephric (Mullerian) ducts give rise to?

A

Uterine tubes
Uterus
Superior vagina

20
Q

What are the three parts of the paramesonephric (Mullerian) ducts?

A

Cranial
Horizontal
Caudal

21
Q

Name the 6 uterine abnormalities

A
Double uterus, double vagina
Double uterus- 2x cervix + uterus
Bicornate uterus- 2x uterus off 1 cervix
Septate uterus
Unicornuate uterus- 1 uterine tube
Cervical atresia- No cervix
22
Q

During what ages are the external genitalia indistinguishable?

A

Weeks 4-7

23
Q

What is hypospadias?

A

External urethral opening not in glans