Embryology Flashcards
From what does the urogenital tract develop?
Intermediate mesoderm
From when does sexual differentiation occur?
7 weeks on
What triggers development of the male genital tract?
Sex determining region of Y (SRY) transcription factor
What do the somatic support cells differentiate into in males?
Sertoli cells
What does the male genital tract develop from?
Mesonephric (Wolffian) duct
What do sertoli cells produce?
Anti-Mullerian hormone
Stim production of Leydig cells
What do Leydig cells produce?
Testosterone
What does testosterone induce?
Formation of epididymis, vas deferens, seminal vesicles
What does Dihydrotestosterone (DHT) induce?
Male specific external genitalia
What does Persistent Mullerian Duct Syndrome produce?
Uterus, vagina and uterine tubes
Testes in ovarian location
Male external genitalia
What is an undescended testes called?
Cryptorchidism
When do male accessory glands develop?
10w
What are the three accessory glands in males?
Bulbourethral and prostate
Seminal vesicle
What stimulates the development of the female genital tract?
Absence of SRY transcription factor
What do somatic support cells differentiate into in females?
Granulosa cells