Embryology Flashcards
embryonic period
characterised by spectacular growth and differentiation of tissues
fetal period
begins after all major organ systems are established and is characterised by growth and maintenance
gametogenesis
stage 1: production of sperm and ova
fertilisation of ovum
stage 2: sperm penetrates ovum and nuclear materials fuse
segmentation/ cleavage
stage 3: rapid division with little growth
gastrulation
stage 4: development of 3 germ layers
- ectoderm
- mesoderm
- endoderm
differentiation
stage 5: development of new cell types
histogenesis
stage 6: creation of cells typical of body tissues
organogenesis
stage 7: formation of recognisable organs
morphogenesis
stage 8: the moulding of the form and shape of the body
cell cycle
produce daughter cells by dividing its DNA and duplicating
G1 phase
metabolic changes prepare the cell for division.
-> at the restriction point- the cell is committed to division and moves to S phase
S phase
DNA synthesis replicated the genetic material
G2 phase
metabolic changes assemble the cytoplasmic materials necessary for mitosis and cytokinesis
M phase
mitosis- nuclear division followed by cell division (cytokinesis)
Mitosis
eukaryotic cell division- the same genetic material as parent produces 2 daughter cells
NOTE: essential for development of growth (tissue repair and cell replacement)
Prophase
centrosome duplicates itself to form 2 daughter centrosomes that migrate to opposite ends of the cell
Prometaphase
- chromosomes migrate to equatorial plane
- spindle fibres bind to kinetochore
- individual spindle fibres bind to a kinetochore structure on each side of the centromere
- chromosomes continue to condense
Metaphase
chromosomes align themselves along metaphase plate
Anaphase
- chromosomes divide
- chromosomes are pulled apart and move to opposite ends of the cell
- separated sister chromatids –> daughter cells
Telophase
- nuclear membrane reforms around chromosomes grouped at wither pole of the cell
- chromosomes uncoil
- spindle fibres disappear
Cytokinesis
- forms two new cells
1. in plants: cell plate forms
2. in animals: there is a constriction of the cytoplasm
Meiosis
produces haploid sex cells (gametes) from diploid cells
1st meiotic division
AKA: reduction division
reciprocal exchange of genetic material between non- sister chromatids
Prophase 1
homologous chromosomes of each pair mate and form TETRADS
Leptotene
(Prophase 1): chromosomes start to condense
zygotene
(Prophase 1): homologous chromosomes become closely associated (synapsis) to form pairs of chromosomes (bivalents) consisting of 4 chromatids (tetrads)