Embryology Flashcards

1
Q

What is the ampulla?

A

site of fertilisation

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2
Q

What is the zona pellucida?

A

Tough protective protein layer surrounding oocyte

- Stops embryo from sticking in the fallopian tube

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3
Q

how does the sperm get through the zona pellucida?

A

acrosomal enzymes are released from the sperm head which digest the zona pellucida

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4
Q

What is a trophoblast?

A

Cells that line the zona pellucida

- Go on to form the placenta

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5
Q

what is the oropharyngeal membrane?

A

Site of future mouth

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6
Q

What is gastrulation?

A

formation of tissue (Germ) layers

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7
Q

What does the term morphogenesis mean?

A

Formation of the body plan (embryonic folding)

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8
Q

Whats is meant by the term induction?

A

The ability one cell type to cause another to differentiate

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9
Q

What does epigenetic mean?

A

Preferential expression of either the maternal or the paternal copy of a gene

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10
Q

On which day is implantation complete

A

Day 9

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11
Q

After gastrulation what does the ectoderm become?

A
  • Epidermis of the skin
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12
Q

After gastrulation what does the endoderm become?

A
  • Lining of the gut tube

- Lining of the respiratory tract

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13
Q

After gastrulation what does the mesoderm become?

A

Mesoderm becomes divided into 3 regions either side of the notochord

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14
Q

3rd month features

A
  • Face more human looking
  • Lengthening of limbs
  • Ossification of long bones and skull
  • Can determine Gender
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15
Q

4th and 5th month

A

Rapid increase in length

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16
Q

6th month –> Birth

A

Rapid increase in weight gain

17
Q

Causes of Defects

A
  • Infectious agent
  • Radiation
  • Chemical agents and prescription drugs
  • Nutritional Deficiencies
  • Maternal Disease
18
Q

What happens during lateral folding

A
  • Converts the open coelom into a closed cavity

- Creates thoracic and abdominal cavities and closing fore and hindgut

19
Q

What happens during Cranial Folding

A

Forms the foregut

Defines the thoracic cavity

20
Q

What happens during caudal folding

A

Cloacal membrane and connecting stalk are displaced ventrally alongside the neck of the yolk sac

Froms:
Hindgut
Anus
And Umbilical Cord

21
Q

When does the heart begin to develop

A

Week 4

22
Q

Name the two cardiac Septa

A
  1. Septum Primum (flexible)

2. Septum Secundum ( more rigid)

23
Q

What happens during probe patent foramen ovale

A
  • Septum prison and septum secundum fail to fuse
  • mixing of blood prevented due to pressure difference

can go entire life without knowing you have this

24
Q

Define Transposition of the great vessels

A

Aorta exits right ventricle
Pulmonary trunk exits left ventricle
Deoxygenated blood pumped around the body

THIS ARRISES DUE TO THE SPIRALLING SEPTUM - IF IT FAILS TO SPIRAL THESE PROBLEMS CAN ARISE

25
Q

What are the four components of TETRALOGY OF FALLOUT

A
  1. Pulmonary Stenosis
  2. Hypertrophy of the left ventricle
  3. VSD
  4. Over - riding aorta