Embryogenesis and development Flashcards
What is the difference between determinate and indeterminate cells?
Determinate cells have already been designated to turn into a type of cell
Indeterminate cells haven’t been designated yet, so they have the ability to become any part of the organism
What are the characteristics of the morula?
Just a mass of cells the looks like a berry
What are the characteristics of the blastula?
A hollow ball of cells with fluid inside, consists of the trophoblast and inner cell mass
The inner cell mass will become the embryo and the trophoblast will become the chorion
What are the characteristics of the gastrula?
This is when the three germ layers form
An invagination of the blastula results in one side of the cell caving in until it touches the other side of the cell, making the tube (anus in humans)
The ability of one cell to influence nearby cells is called _____
Induction
(cells that create induction are called inducers)
The umbilical cord has ___ artery (ies) and ___ vein(s)
2 arteries
1 vein
What is the ectoderm and what are some structures it makes up?
The outer most layer
Many “outer” structures:
hair, nails, inner ear, nervous system, eye lens, lower anus, epidermis
What is the mesoderm and what are some structures it makes up?
The middle layer
Musculoskeletal system, muscular and connective tissue, layers of digestive and respiratory system, adrenal cortex
What is the endoderm and what are some structures it makes up?
The inner most layer
Epithelial lining of digestive and respiratory system, pancreas, thyroid, bladder, distal urinary tract, parts of the liver
How does neurulation occur?
The notochord (made of mesoderm) forces the ectoderm to start folding inward, forming the neural folds. Eventually the neural folds become the neural tube
Then the crest cells migrate out and become the peripheral nervous system
The notochord is made of _____ while the nervous system is made of ____
Mesoderm
Ectoderm
Explain how the three stages of development (specification, determination, differentiation) occur
Specification is reversible and is the point where cells are designated to become a certain type
Determination is irreversible and occurs when the cells have been committed to a certain type, but haven’t undergone any changes yet
Differentiation occurs when the cell changes it’s structure, function and biochemistry to match the cell type
Stem cells are those that have not ____
Undergone differentiation, or have the ability to give rise to other cells
Totipotent cells
Have the highest level of potency
They’re still in the morula phase, so they can become literally anything
Found from fetal stem cells
Pluripotent cells
Have the middle level of potency
They’ve already reached the gastrula stage (differentiated into germ layers) so they can become anything other than placental cells
Multipotent cells
Have the lowest level of potency (adult stem cells)
Can become multiple cells within a certain group. The class they’re in has already been decided (ex: immune cells) so they can only be used to create cells of that same category
Autocrine
Acts on the same cell that secreted the signal
Endocrine
Travels through the blood is reach the target cells
Juxtacrine
Acts directly on adjacent cells, does not work through diffusion
Paracrine
Works on nearby cells through diffusion
What is the difference between complete and incomplete regeneration?
Complete regeneration occurs when the newly formed tissue is identical to the original
Incomplete regeneration occurs when the newly formed tissue is different than the original (ex: scar tissue)
Why would cells need to migrate?
So they’re able to reach the necessary location for their designated purpose
Senescence
Normal cell aging (this kind of cell will eventually hit apoptosis)
In what trimester does most organ development occur?
First
The ____ are the last organ to develop
Lungs
The foramen ovale and ductus arteriosus shunt blood away from the ____
Lungs
What is the purpose of the placenta?
Exchanges gas, nutrients, and waste
Gets necessary things from mother so fetal and maternal blood don’t have to mix (these two cannot mix)
The ductus venosus shunts blood away from the ____
Liver
The most fetal movement occurs during the ____
Second trimester
Antibody transfer occurs at the highest rate in the ____ trimester
Third trimester