Embryo3 Flashcards

1
Q

Paraxial Mesoderm derivatives

A

Vertebrae
Annulus fibrosus of intervertebral discs
Ribs
Neurocranium (occipital, parietal, petrous, posterior sphenoid)

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2
Q

Lateral Plate Mesoderm derivatives

A

Pectoral girdle
Pelvic girdle
Limbs
Sternum (axial skeleton)

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3
Q

Neural crest cell derivatives

A
Viscerocranium and hyoid bone
Neurocranium:
(Frontal bone
Squamous portion of temporal
Anterior sphenoid)
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4
Q

Viscerocranium comes from ______ ossification

A

intramembranous

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5
Q

Chondrocranium comes from _____ ossification

A

Endochondral

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6
Q

Endochondral Ossification before birth

A

Early cartilage model
Primary ossification center
Secondary ossification center (vascular)

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7
Q

Intramembranous ossification

A

Mesenchyme condenses
Osteoblast/clast
Bony spicules
Reorganize as osteons

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8
Q

Chondrocranium includes

A

sphenoid
Petrous portion of temporal
Portion of occipital

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9
Q

Fontanell

A

enlarged membranous space where more than 2 bones meet

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10
Q

Largest Fontanelle

A

Anterior Fontanelle

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11
Q

Scaphocephaly

A

premature closing of sagittal suture

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12
Q

Brachycephaly

A

premature closing of coronal suture

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13
Q

Paraxial mesoderm (sclerotome) forms all axial skeleton except

A

sternum and portion of skull

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14
Q

Chondrification occurs at

A

6 weeks

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15
Q

Ossification occurs at

A

7 weeks

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16
Q

Ribs are lateral extension of

A

Costal processes of thoracic vertebrae

17
Q

Sternum develops during ___ week from

A

10th week from lateral plate somatic mesoderm

18
Q

Week 6 appendicular skeleton

A

Mesenchymal bone models undergo chondrification to form hyalline cartilage

19
Q

Achondroplasia

A

Most common skeletal dysplasia

distubance of endochondral ossification during fetal life at epiphyseal cartilage plates esp long bones

20
Q

Skeletal muscle derived from

A

paraxial mesoderm

21
Q

Cardiac muscle derived from

A

intraembryonic splanchnic mesoderm

22
Q

Smooth muscle derived from

A

intraembryonic splanchnic mesoderm

23
Q

Somites give rise to (3)

A

axial skeleton
Associated musculature (bold)
Overlying dermis of back

24
Q

Myoblasts
definition
Actively contract at

A

specialized mesoderm cells that fuse together to form skeletal muscle
Actively contract at 7 weeks

25
Meromelia
absense of part of limb
26
Amelia
absence of entire limb
27
Polydactyly
extra digits
28
Syndactyly
few digits
29
Week 12
primary ossification centers in all long bones
30
At birth
diaphysis completely ossified, epiphyses still cartilaginous
31
Primaxial forms
Epaxial muscles: back intercostals shoulder girdle
32
Abaxial forms
``` Hypaxial muscles: infrahyoid m. pectoralis M and m mm. body wall mm. limb mm. ```
33
Ectoderm derived smooth muscle
Neuroectoderm: sphincter pupillae, dilator pupillae | Surface ectoderm: myoepithelial ells of mammary, salivary, sweat glands
34
Limb buds emerge near end of __ week
4th week
35
_______ sends signaling factors to nearby mesenchyme of ________ zone
Apical ectodermal ridge to progress zone
36
Limb rotation
week 7