EM neonatology Flashcards
Phrenic nerve injury is due to overstretching of the anterior roots of ______. This results from lateral hyperextension of the neck, especially during breech births or difficult forceps delivery
cervical nerves 3, 4 and 5
MSAFP can be elevated in _____
open neural tube defects, bowel malformations
MSAFP is high and the ACE is normal, there may be a malformation other than an open neural tube defect. The most probable cause of these labs is the
omphalocele, in which the bowel protrudes into a sac extending off of the fetal abdomen. This malformation can be easily identified during a sonographic examination.
Endotracheal intubation and suction should be done first to remove any meconium that is present in the trachea before giving positive pressure ventilation.
Nasopharyngeal suction and tactile stimulation will push the meconium present in the trachea into the lungs and can cause aspiration pneumonia.
What is the most common neuronal injury in brachial plexus…
neuropraxia, involves damage to the nerve sheath alone and is associated with interruption in conduction of impulses down the nerve fiber resulting in a temporary conduction block. Complete spontaneous recovery with 90% to 100% return of function usually occurs.
In neonatal CMV infection findings at the time of diagnosis in the newborn period that are predictors for long-term poor neurologic and developmental outcomes include
intracranial abnormalities on CT scan, especially calcifications, CSF protein concentrations greater than 120 mg/dl, and placentomegaly.
Management of suspected brachial plexus injury requires gentle handling of the affected limb, radiographs of the clavicle and humerus to exclude bony injury, observation for respiratory distress indicating diaphragmatic injury, and referral to
physical therapists for passive range of motion exercises including the neck and proximal arm beginning 7 to 10 days after birth.
Clubfoot, or talipes equinovarus, is a congenital foot disorder characterized by plantar flexion of the ankle, adduction of the heel, high midfoot arches, and adduction of the forefoot. Treatment consists of
manipulation and casting and it should be initiated immediately upon diagnosis. Two to four months of serial casting and manipulation are often needed to correct a clubfoot.
Children born to _____ mothers show prenatal and postnatal growth problems, mental retardation, maxillary hypoplasia, congenital heart disease, and abnormal palmar creases.
Alcohol is the most common drug that is abused during pregnancy.
______ causes congenital problems in the heart and great vessels.
Lithium carbonate is used for bipolar problems (Ebstein’s anomaly)
______ causes a multitude of abnormalities with emphasis on skeletal, face, skull, limbs, and vertebral column.
Methotrexate
______ can cause varying degrees of masculinization of the female fetus. The ambiguous external genitalia can have fused labia and clitoral hypertrophy.
Testosterone, ethisterone, and norethisterone
____ results in a wide range of skeletal, CNS, and growth problems.
Aminopterin
Stunted growth, skeletal anomalies, corneal opacities, cleft palate, and hypoplasia of organs can be seen with
busulfan.
____ induces skeletal malformations as well as external ear, cardiac, and GI malformations.
Thalidomide. This drug is a potent teratogen and is used as a tranquilizer or sedative.