Electron Transport Chain

Question 1

Complex 1

Answer 1

NADH-CoQ oxidoreductase

NADH + H + CoQ —> NAD+ + CoQH2
1 ATP

Question 2

Complex 2

Answer 2

Succinate-CoQ oxidoreductase

Succinate + CoQ —> Fumarate + CoQH2

Question 3

Complex 3

Answer 3

CoQH2 - cytochrome C oxidoreductase

CoQH2 + 2 cyt C (Fe3+) —> CoQ + 2Cyt C (Fe2+) + 2H+
0.5 ATP
Q cycle

Question 4

Complex 4

Answer 4

Cytochrome oxidoreductase

2 cyt c (Fe2+) + 2H+ + 0.5O2 —> 2cyt C (Fe3+) + H2O
1 ATP

Question 5

Electron transport chain

Answer 5

Voltage and pH gradient

Question 6

ETC mechanism

Answer 6

Chemiosmotic coupling

Conformational coupling

Question 7

Uncoupler

Answer 7

Compound which inhibit phosphorylation of ATP without affecting electron transport

Question 8

Respiratory inhibitors

Answer 8

Complex 1: Amytal (barbiturate)
Complex 3: Antimycin A (antibiotic)
Complex 4: cyanide (CN-)