ELECTROLYTES Flashcards
What are the electrolytes that have a high concentration in RBCs?
- Potassium
- Phosphorus
- Magnesium
What are the electrolytes that have a high concentration in the plasma?
- Sodium
- Chloride
Sodium and chloride have a high concentration in what?
high concentration in the plasma
Potassium, phosphorus, and Magnesium have a high concentration in what?
high concentration in RBCs
These are ions that carry a negative charge
Anions
Anions carry what charge?
negative charge
These ions move toward the anode
Anions
Anions move toward what field?
the anode
The anode is a field with what charge?
positively charged field
This is a positively charged field
anode
Anions move toward the positively charged field
true or false
true
What are examples of anions?
- Choride
- Bicarbonate
- Phosphate
These are ions that carry a positive charge
cations
cations move toward what field?
cathode
This is a negatively charged field
cathode
a cathode has a field of what charge?
a negatively charged field
cations carry what charge?
cations carry a positive charge
What are examples of cations?
- Sodium
- Potassium
- Magnesium
- Calcium
Chloride is an anion
true or false
TRUE
Sodium is an anion
true or false
FALSE
Cation
Sodium is an anion
true or false
FALSE
Cation
Bicarbonate is an anion
true or false
True
Potassium is an anion
true or false
false
cation
Phosphate is an anion
true or false
true
Phosphate is not an anion
true or false
false
anion
Magnesium is an anion
true or false
false
cation
Magnesium is an anion
true or false
false
cation
Calcium is an anion
true or false
False
cation
Calcium is an anion
true or false
False
cation
chloride
Anion or cation
Anion
Bicarbonate
Anion or cation
Anion
Phosphate
Anion or cation
Anion
Sodium
Anion or cation
Cation
Potassium
Anion or cation
Cation
Magnesium
Anion or cation
Cation
Calcium
Anion or cation
Cation
What are 7 functions of electrolytes?
“Important For the Regulation , For the Production, and Maintenance of Volume For Neuromuscular Excitability and Myocardial Rhythm”
- Important cofactors in enzyme activation
- For the regulation of adenosine triphosphatase (ATPase) ion pumps
- For the production and use of ATP from glucose
- Maintenance of acid-base balance
- Volume and osmotic regulation
- For Neuromuscular Excitability
- Myocardial rhythm and contractility
What are the electrolytes for the volume and osmotic regulation?
Na, Cl, K
What are the electrolytes for Myocardial rhythm and contractility?
Mg, K, Ca
What are the electrolytes for important cofactors in enzyme activation?
Mg, Ca, Zn
What are the electrolytes for the regulation of adenosine triphosphatase (ATPase) ion pump?
Mg
What are the electrolytes for the neuromuscular excitability?
Same as Myocardiam Rhthym and contactility
Mg, K, Ca
What are the electrolytes for the production and use of ATP from glucose?
plus ATPase ion pump
Mg and PO4
What are the electrolytes for maintenance of acid-**base **balance?
HCO3, K, Cl
It is the major extracellular anion
Chloride
Chloride promotes the maintenance of what?
promotes maintenance of water balance and osmotic pressure
Chloride promotes maintenance of water balance and osmotic pressure in conjunction with what?
in conjunction with sodium
It promotes maintenance of water balance and osmotic pressure in conjunction with sodium
Chloride
Chloride is the major extracellular anion-chief counter ion of WHAT in WHERE?
the major extracellular anion-chief counter ion of sodium in ECF
It is the only anion to serve as an enzyme activator
Chloride
Chloride is the only anion to serve as a/an what?
to serve as an enzyme activator
This electrolyte has a reference value of 98-107 mmol/L
Chloride
What is the reference value of chloride?
98-107 mmol/L
What is the normal range for chloride in the urine?
110-250 mmol/ day, varies with diet
this electrolyte varies with diet in the urine
chloride
Marked hemolysis may cause decreased levels of chloride due to what?
due to dilutional effect
In chloride specimen consideration, slightly lower values are observed in what kind of specimen?
post prandial specimen
In chloride specimen consideration, low serum values are observed in conditions with what?
high HCO3 levels
In chloride specimen consideration, this may cause decreased levels of chloride due to dilutional effect
Marked hemolysis
In chloride specimen consideration, marked hemolysis may cause what to the levels of chloride due to dilutional effect?
decreased levels
In chloride specimen consideration, what is observed in post prandial specimens?
Slightly lower values
In chloride specimen considerations, these are observed in conditions with high HCO3 levels
Low serum values
Lower values are observed in post prandial specimens in chloride specimen considerations
true or false
slightly low values
false
High serum levels are observed in conditions with high HCO3 levels in chloride specimen considerations
true or false
Low serum levels
false
High serum levels are observed in conditions with high HCO3 levels in chloride specimen considerations
true or false
Low serum levels
false
Marked hemolysis may cause increased levels of chloride due to dilutional effect
true or false
decreased levels of chloride
false
Marked hemolysis may cause increased levels of chloride due to dilutional effect
true or false
decreased levels of chloride
false
What is the anticoagulant of choice for chloride?
lithium heparin
Lithium heparin is the anticoagulant of choice for what electrolyte?
chloride
In chloride, marked hemolysis may cause levels to be decreased as a result of what?
as a result of dilutional effect
In the urine specimen for chloride, this is needed because of the large diurnal variation
24-hour collection
In the urine specimen for chloride, why is a 24-hour collection needed?
needed because of the large
diurnal variation
In the urine specimen for chloride, why is a 24-hour collection needed?
needed because of the large
diurnal variation
What are the methods used for chloride?
- Ion Selective Electrode (ISE)
- Mercurimetric Titration
- Colorimetry
This is a solid-state electrode using membranes composed of AgCl
ISE
ISE is a solid-state electrode using membranes composed of what?
AgCl
In this method for chloride, in the presence of Cl¯ anions, an oxidation reduction reaction occurs, silver metal forms Ag+ cation and electrons
ISE
In ISE in Cl, what occurs in the presence of Cl- anions?
an oxidation reduction reaction
In ISE, an oxidation reduction reaction occurs in the presence of what?
in the presence of Cl- anions
When an oxidation reduction reaction occurs, silver metal forms what?
silver metal forms Ag+ cation and electrons
Mercurimetric titration is also called …
Schales and Schales method
Schales and Schales method is also called …
mercurimetric titration
What is the principle in Mercurimetric titration?
- Cl- in the sample combines with the added Hg++ to form the soluble HgCl2 complex.
- Excess unreacted added Hg++ combines with an indicator such as diphenylcarbazone to form a blue violet/purple end point of titration
In Schales and Schales method, the Cl- in the sample combines with added Hg++ to form what?
to form the soluble HgCl2 complex
Excess unreacted added Hg++ combines what an indicator such as what?
such as diphenylcarbazone
Excess unreacted added Hg++ combines with an indicator such as diphenylcarbazone to form a what?
to form a blue-violet/purple end point of titration
Excess unreacted added Hg++ combines with a what?
combines with an indicator
What is the endpoint/end product of mercurimetric titration?
blue-violet/purple
Colorimetry method in chloride is by …
Schoenfeld and Lewellen
Schoenfeld and Lewellen demonstrated what method?
colorimetry
What is the principle of Schoenfeld and Lewellen?
- Cl- ions in serum displaced thiocyanate ions from mercuric thiocyanate forming = mercuric chloride, which is only very slightly ionized
- The liberated thiocyanate ions react with ferric ions to form = the orange-yellow thiocyanate complex, which is measured at 550nm against a water blank
In the colorimtery method, Cl- ions in serum displaces what?
displaces thiocyanate ions
In the colorimtery method, Cl- ions in serum displaces thiocyanate ions from what?
from mercuric thiocyanate
In the colorimtery method, Cl- ions in serum displaces thiocyanate from mercuric thiocyanate forming what?
forming mercuric chloride
the mercuric chloride formed from the displacement of thiocyanate from mercuric thiocyanate is only slightly ionized
true or false
VERY slightly ionized
false
the mercuric chloride formed from the displacement of thiocyanate from mercuric thiocyanate is only slightly ionized
true or false
VERY slightly ionized
false
In Schoenfeld and Lewellen, these react with ferric ions to form the orange-yellow thiocyanate complex?
liberated thiocyanate ions react with ferric ions
In colorimetry method in chloride, the liberated thiocyanate ions react with what?
react with ferric ions