Elderly- Pathophysiology of ageing Flashcards
1
Q
What are the 3 types of ageing?
A
Stochastic
Programmed
Homeostatic failure
2
Q
What is stochastic ageing due to?
A
Cumulative damage
3
Q
What is stochastic ageing due to?
A
Cumulative damage
4
Q
What is programmed ageing due to?
A
Ageing is predetermined in gene expression
5
Q
What is frailty in terms of homeostasis?
A
Dyshomeostasis
6
Q
What is social dyshomeostasis?
A
Loss of ability to compensate for (emotional) events
7
Q
What are the beneficial aspects of ageing?
A
Experiential learning
8
Q
What are the neutral impacts of ageing?
A
Grey hair
9
Q
What are the detrimental aspects of ageing?
A
Hypertension
Decreased balance
10
Q
What are the practical implications of ageing?
A
- More people with co-mobordities
- Greater inter-individual variability in function/reserve
- Mixed up diseases presenting very similarly
- Little evidence e.g. drug trials in >80s (because its hard)
- Polypharmacy –> More ADRs & Drug interactions
