Efferent Somatic & Autonomic NS Flashcards
Pathway Damage
Unlike skeletal muscle, tissues innervated by the ANS often function
to some extent if their nerve supply is damaged or cut
Spinal Nerves
- Cervical Nerves – 8 Pairs
- Thoracic Nerves – 12 Pairs
- Lumbar Nerves – 5 Pairs
- Sacral Nerves – 5 Pairs
- Coccygeal Nerves – 1 Pair
Motor Cortex
For the cerebral cortex to perform its motor
functions, impulses must be conducted
from its motor areas to skeletal muscles by
relays of neurons referred to as
Somatic Motor Pathways
Wilder Penfield
used electrical stimulation to map the cortices of
patients who were about to undergo neurosurgery
Final Common Pathway (Sherrington)
Lower Motor Neurons receive excitatory/inhibitory synaptic inputs from Upper Motor Neurons of supraspinal origin either directly or via interneurons
Autonomic Nervous System: Anatomy
Both divisions of the ANS share the same general structure
Autonomic pathways always consist of two neurons in series
They synapse in an autonomic ganglion
The first neuron in the autonomic pathway is the pre-ganglionic neuron
• Cell body in CNS, myelinated and projects to the autonomic ganglion
While the second neuron is the post-ganglionic neuron
• Cell body in autonomic ganglion, unmyelinated and projects to the effector
Sympathetic Division: Anatomy
Pre-ganglionic sympathetic fibres are short
Pre-ganglionic sympathetic fibres release acetylcholine (ACh) at ganglia
Post-ganglionic sympathetic fibres are long
Post-ganglionic sympathetic fibres release noradrenaline (NA) in most cases
and the effect can be stimulatory or inhibitory
Response of target organ is dependent upon the receptor type(s) expressed
Adrenal Gland - The exception
• Pre-ganglionic fibers will pass through sympathetic ganglia without synapsing • Pre-ganglionic fibers will synapse on adrenal medulla
CRANIAL OUTFLOW
III Oculomotor VII Facial IX Glossopharyngeal X Vagus (major pre-ganglionic supply to thorax and abdomen) - Synapse in ganglia within wall of the target organ -parasympathetic NS
SACRAL OUTFLOW
- S2-S4 via pelvic splanchnic nerves - Gut, pelvic viscera and external genitals -parasympathetic NS
Parasympathetic Division: Anatomy
Pre-ganglionic parasympathetic fibres are long
Pre-ganglionic parasympathetic fibres release acetylcholine (ACh) at ganglia
Post-ganglionic parasympathetic fibres are short
Post-ganglionic parasympathetic fibres release ACh and the effect can be
either stimulatory or inhibitory
Response of target organ is dependent upon the receptor type(s) expressed
Antagonistic Control
Parasympathetic and Sympathetic stimulation have opposite impacts on effectors