Effectors I Flashcards
I. Vertebrate Muscle Types
A. Smooth Muscle - lines blood vessels, organs
- autonomic control
B. Cardiac Muscle - heart
C. Striated Muscle - skeletal muscle (e.g. limbs)
- under voluntary control (driven by motor neurons)
Effectors I
I. Vertebrate Muscle Types
II. Skeletal Muscle
III. Sliding Filaments
II. Skeletal Muscle
A. Tissue diagram B. Muscle Fiber diagram C. Myofibril diagram: contraction 1) z line closer together 2) I bands and H zones get narrower 3) a bands remains same
III. Sliding Filaments
parts
A. Filament Structure
B. Molecular Mechanism
III. Sliding Filaments
A. Filament Structure
diagram: myosin filaments
Figure 39.2 Structure of skeletal muscle
Figure 39.3 Sliding Filament model of muscle contraction
diagram: myosin diagram:
contraction- produced by pulling actin PAST myosin; draws z lines closer
III. Sliding Filaments
B. Molecular Mechanism
- Energy: ATP -> ADP +Pi
- Myosin uses energy to form CROSS-BRIDGES to actin and pull
two diagrams - “Ratchet” Mechanism:
III. Sliding Filaments
B. Molecular Mechanism
3. “Ratchet” mechanism
a) MYOSIN head binds to ATP
- > cleaves to ADP (still bound)
- > becomes ACTIVATED (“cocked”)
b) when actin is “EXPOSED” activated myosin binds & forms “cross bridges”
c) energy from ATP cleavage is released as:
1) myosin head springs back to original position, moving the BOUND actin &
2) releases ADP
d) myosin binds a new ATP & releases old cross bridge -> repeats cycle
Figure39.4 Myosin -Actin Interactions underlying muscle contraction
about 350 head groups per myosin filament
each head group makes about 5 cross-bridges during contraction
about ___ head groups per myosin filament
350
Each head group makes about ___ cross-bridges during contraction
5