EBV

Question 1

What are 50% of EBV cases?

Answer 1

asymptomatic

Question 2

What has EBV been linked to?

Answer 2

neurologic sequelae, lymphoproliferative and neoplastic diseases

Question 3

How is EBV spread?

Answer 3

oropharyngeal secretions, blood transfusions

Question 4

What age has highest rate of EBV?

Answer 4

15-24 yo

Question 5

What is the incubation for EBV?

Answer 5

4-6 wks

Question 6

How does EBV present in young and infants?

Answer 6

mild pharyngitis

Question 7

How does acute IM present?

Answer 7

posterior lymph nodes, fever, fatigue, myalgia, pharyngitis, splenomegaly and hepatomegaly, tonsillitis, morbilliform rash

Question 8

What do you not give with EBV?

Answer 8

cillin abx - causes rash

Question 9

How do you dx?

Answer 9

rapid mono - detects IgM - heterophile 90% pts

Question 10

When do heterophile peak?

Answer 10

2-6 wks after infection

Question 11

What will you see on CbC?

Answer 11

leukocytosis, lymphocytosis, atypical lymphocytes

Question 12

What will you see on CMP?

Answer 12

elevated aminotransferases, elevated alkaline phosphatase, elevated bilirubin

Question 13

What is the tx?

Answer 13

avoid abx, self limiting

Question 14

When do you use prednisone?

Answer 14

tonsillar hypertrophy

Question 15

What should EBV pt avoid?

Answer 15

strenuous activity for 4 wks - could rupture spleen

Question 16

When do neuro symp develop?

Answer 16

first 2 wks

Question 17

What are the neuro symptoms?

Answer 17

meningitis, encephalitis, HA, ataxia, meningismus,

Question 18

What is associated with HIV pt with EBV?

Answer 18

hairy leukoplakia

Question 19

What cancers are associated with EBV?

Answer 19

burkitt’s lymphoma, anaplastic nasopharyngeal carcinoma, gastric carcinoma, hodgkin’s disease