early pregnancy Flashcards
chadwick sign
vaginal/cervical purple blue colour can indicate pregnancy
what antibody can pass through the placenta
IgG
what does HCG do
prevents involution of corpus luteum
develops testes in males
what does Human Chorionic somatomammotropin do
produced from week 5 of pregnancy
decrease insulin sensitivity in mother= increased glucose for baby
what does progesterone do
decrease uterus contractibility
preps for lactation
stimulates breast lobules
smooth muscle relaxant
what does oestrogen do
increase size of uterus
develops ductal system
decrease FSH and LH production
thins cervical mucous
drugs to avoid during breast feeding
phenobarbitone
amiodarone
benzodiazepines
bromocriptine
cytotoxics
tetracycline and doxycycline
what does folic acid do during pregnancy
helps to prevent microcephaly and neural tube defects (spina bifida)
when would you prescribe a higher dose of folic acid to the mum
previous NTD
taking anti-epileptics
coeliac disease
diabetes
thalassaemia trait
BMI >30
what would you prescribe for hypertension in pregnancy
labetalol
what would you prescribe for nausea and vomiting in pregnancy
cyclizine
what would you prescribe for a UTI in pregnancy
1st or 2nd trimester: nitrofurantoin
3rd trimester: trimethoprim
what would you prescribe for heartburn in pregnancy
antacids or omeprazole
what would you prescribe for DVT or PE risk in pregnant woman
Low Molecular Weight Heparin
definition of small for gestational age
abdominal circumference (or estimated fetal weight) less than the 10th centile
severe= < 3rd centile
