(E1) 4 - Odontogenesis Pt II: Crown Formation Flashcards

Exam 1 - BLANKENSHIP

1
Q

Genetic disorder leading to abnormal enamel functions

A

Amelogenesis imperfecta

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2
Q

Genetic disorders leading to abnormal dentin formation

A

Dentinogenesis imperfecta

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3
Q

3 components of a tooth

A

Enamel
Dentin
Pulp

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4
Q

Describe Enamel

A
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5
Q

Describe Dentin

A
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6
Q

When is size and shape of tooth set?

A

Cap stage

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7
Q

In the crown stage, changes are associated with

A
  • Amount and type of hard tissue mineralization
  • Reduction of some tooth germ structures
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8
Q

In the late bell stage, signals from the enamel knot cause what?

A
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9
Q

Odontoblast differentiation occurs because of signals from ________

A

IEE

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10
Q

What are the functions of mature odontoblasts?

A
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11
Q

What is the first step in dentinogenesis?

A

Pre-Dentin Deposition

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12
Q

Describe Primary Dentin

A
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13
Q

When does secondary dentin form?

A

After eruption
- Includes radicular dentin and circumpulpal

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14
Q

What is mantle dentin?

A

First pre-dentin to be secreted and mineralized (closest to the DEJ)

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15
Q

What is the second stage of dentinogenesis?

A
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16
Q

What is the third stage of dentinogenesis?

A
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17
Q

Stages of Development: Crown Stage

What is the functional stage and morphological appearance?

A

Functional = Apposition
Morphological = Hard tissues of crown visible

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18
Q

What are ameloblasts?

A

Ectoderm-derived epithelial cells of the inner enamel epithelium

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19
Q

Where does the deposition of the dentin matrix begin and end?

A

Begins at the future cusps along DEJ, continues towards the cervical loop

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20
Q

Crown Stage: Describe what is happening during the initiation of the crown stage.

A
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21
Q

What is happening during ameloblast maturation?

22
Q

As reduction of the enamel organ occurs, what forms?

23
Q

What are the 4 stages of amelogenesis?

A

1 - Presecretory (inductive)
2 - Secretory
3 - Maturation
4 - Protective

24
Q

Amelogenesis: Describe what is happening in the Pre-Secretory stage.

25
Q

Amelogenesis: Describe what is happening in the Secretory stage.

26
Q

Amelogenesis: Describe what is happening in the Maturation stage.

27
Q

Amelogenesis: Describe what is happening in the Protective stage.

28
Q

Image of Amelogenesis

29
Q

Synthesis and secretion of Enamel ECM (secretory stage): What are the cells involved and the function?

30
Q

What are the types of secretory ameloblasts and what are the resulting types of enamel?

31
Q

Amelogenesis - Describe:

32
Q

How might a mutation in the genes responsible for encoding organic matrix proteins affect amelogenesis?

33
Q

Amelogenesis - Describe:

33
Q

Deposition and orientation of enamel crystals depend on the presence of a ___________

A

Tome’s process

34
Q

Describe Aprismatic enamel

35
Q

What are the 3 orientations of enamel crystals?

A
  • Aprismatic
  • Prismatic/Rod enamel
  • Inter-prismatic/Interrod
36
Q

Amelogenesis - Describe:

37
Q

What are the 2 types of mature ameloblasts?

A

Ruffled and Smooth

38
Q

Amelogenesis: Function of ruffle ended cells

A
  • incorporation of inorganic (mineral) content
39
Q

Amelogenesis: Function of smooth ended cells

A
  • removal of organic material (proteins) and water by enzymatic digestion
  • changes in pH changes shape
40
Q

All hard tissue (bone, enamel, dentin, cementum) is deposited incrementally in
successive layers by ____________

A

appositional growth

(result - lines visible)

41
Q

Amelogenesis - Describe: (cells involved and function)

42
Q

What composes the reduced enamel epithelium?

43
Q

As tooth erupts, REE fuses with oral
epithelium and becomes __________

A

junctional epithelium

44
Q

What two layers fuse together and form HERS?

A

IEE and OEE

45
Q

What does HERS signify?

A

Signifies the end of the crown and the start of root formation

46
Q

Describe Early Crown

47
Q

Describe Mid Crown

48
Q

Describe Late Crown

49
Q

Describe how you know when the crown is complete.