(E1) 4 - Odontogenesis Pt II: Crown Formation Flashcards
Exam 1 - BLANKENSHIP
Genetic disorder leading to abnormal enamel functions
Amelogenesis imperfecta
Genetic disorders leading to abnormal dentin formation
Dentinogenesis imperfecta
3 components of a tooth
Enamel
Dentin
Pulp
Describe Enamel
Describe Dentin
When is size and shape of tooth set?
Cap stage
In the crown stage, changes are associated with
- Amount and type of hard tissue mineralization
- Reduction of some tooth germ structures
In the late bell stage, signals from the enamel knot cause what?
Odontoblast differentiation occurs because of signals from ________
IEE
What are the functions of mature odontoblasts?
What is the first step in dentinogenesis?
Pre-Dentin Deposition
Describe Primary Dentin
When does secondary dentin form?
After eruption
- Includes radicular dentin and circumpulpal
What is mantle dentin?
First pre-dentin to be secreted and mineralized (closest to the DEJ)
What is the second stage of dentinogenesis?
What is the third stage of dentinogenesis?
Stages of Development: Crown Stage
What is the functional stage and morphological appearance?
Functional = Apposition
Morphological = Hard tissues of crown visible
What are ameloblasts?
Ectoderm-derived epithelial cells of the inner enamel epithelium
Where does the deposition of the dentin matrix begin and end?
Begins at the future cusps along DEJ, continues towards the cervical loop
Crown Stage: Describe what is happening during the initiation of the crown stage.
What is happening during ameloblast maturation?
As reduction of the enamel organ occurs, what forms?
HERS
What are the 4 stages of amelogenesis?
1 - Presecretory (inductive)
2 - Secretory
3 - Maturation
4 - Protective
Amelogenesis: Describe what is happening in the Pre-Secretory stage.
Amelogenesis: Describe what is happening in the Secretory stage.
Amelogenesis: Describe what is happening in the Maturation stage.
Amelogenesis: Describe what is happening in the Protective stage.
Image of Amelogenesis
Synthesis and secretion of Enamel ECM (secretory stage): What are the cells involved and the function?
What are the types of secretory ameloblasts and what are the resulting types of enamel?
Amelogenesis - Describe:
How might a mutation in the genes responsible for encoding organic matrix proteins affect amelogenesis?
Amelogenesis - Describe:
Deposition and orientation of enamel crystals depend on the presence of a ___________
Tome’s process
Describe Aprismatic enamel
What are the 3 orientations of enamel crystals?
- Aprismatic
- Prismatic/Rod enamel
- Inter-prismatic/Interrod
Amelogenesis - Describe:
What are the 2 types of mature ameloblasts?
Ruffled and Smooth
Amelogenesis: Function of ruffle ended cells
- incorporation of inorganic (mineral) content
Amelogenesis: Function of smooth ended cells
- removal of organic material (proteins) and water by enzymatic digestion
- changes in pH changes shape
All hard tissue (bone, enamel, dentin, cementum) is deposited incrementally in
successive layers by ____________
appositional growth
(result - lines visible)
Amelogenesis - Describe: (cells involved and function)
What composes the reduced enamel epithelium?
As tooth erupts, REE fuses with oral
epithelium and becomes __________
junctional epithelium
What two layers fuse together and form HERS?
IEE and OEE
What does HERS signify?
Signifies the end of the crown and the start of root formation
Describe Early Crown
Describe Mid Crown
Describe Late Crown
Describe how you know when the crown is complete.