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Sp24 - Oral Histology and Embryology > (E1) 3 - Odontogenesis Pt I: Early Tooth Formation > Flashcards

(E1) 3 - Odontogenesis Pt I: Early Tooth Formation Flashcards

Exam 1 - BLANKENSHIP

1
Q

Mandibular and maxillary arches arise primarily from the ____ with small contribution from ______

A

PA1
Frontonasal proess

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2
Q

Maxillary premolars and molars arise from ___________

A

maxillary process of PA 1

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3
Q

Where do all mandibular teeth arise from?

A

Mandibular process of PA1

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4
Q

Where do maxillary incisors arise from?

A

Frontonasal region (intermaxillary segment)

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5
Q

The early established oral cavity is lined by stratified squamous epithelium called the _______________

A

oral ectoderm

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6
Q

Epithelium covers the embryonic connective tissue called ____________

A

ectomesenchyme

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7
Q

What is ectomesenchyme made up of?

A

Derived from neural crest cells mixed with mesenchyme

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8
Q

~5-6 weeks of gestation, basal cells of the oral ectoderm proliferate faster creating a thickened band called the
_________________

A

Primary epithelial band

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9
Q

What does the primary epithelial band indicate?

A

Position of future dental arches

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10
Q

The primary epithelial band gives rise to two subdivisions. What are they?

A

Dental Lamina
Vestibular Lamina

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11
Q

What is the dental lamina?

A
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12
Q

What is the vestibular lamina?

A
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13
Q

In what direction does the formation of future dental arches occur?

A

Begins anterior and progresses posterior.

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14
Q

All teeth (and appendages) develop from two germ layers. What are they?

A

Oral Ectoderm
Ectomesenchyme

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15
Q

What is oral ectoderm?

A
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16
Q

What is ectomesenchyme?

A
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17
Q

What tooth structure does the epithelium (oral ectoderm) form?

A

Enamel

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18
Q

What tooth structures does the ectomesenchyme form?

A

Dentine, pulp, periodontal ligament, cementum, alveolar bone proper

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19
Q

___________ occurs between dental epithelium and ectomesenchyme → controls dental development

A

Reciprocal signaling

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20
Q

What steps of reciprocal signaling is ectoderm directed?

A

Inititaion

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21
Q

What steps of reciprocal signaling is ectomesenchyme directed?

A

Patterning and Morphogenesis

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22
Q

Reciprocal Signaling: Describe Initiation

A
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23
Q

Reciprocal Signaling: Describe Patterning

A
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24
Q

Reciprocal Signaling: Describe Morphogenesis

A
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25
Chart Image - Germ Layer and Structures
26
What are the 3 parts of the tooth germ?
Enamel Organ Dental Papillae Dental Follicle
27
What is the tooth germ responsible for?
Forms the mature tooth
28
What germ layer is the enamel organ from?
Ectoderm
29
What germ layer are the dental papillae and dental follicles from?
Ectomesenchyme
30
What does the enamel organ give rise to?
Enamel
31
What does the dental papilla give rise to?
Dentin and Pulp
32
What does the dental follicle give rise to?
Cementum PDL Alveolar Bone
33
______________ within primary epithelial band are thought to play a major role in tooth site initiation
Placodes (thickening epithelium)
34
What are the signal types that affect placodes?
Stimulatory Inhibitory Regulatory
35
Defects in signaling pathways lead to _____________ (3 things)
36
What does tooth type mean?
37
What does tooth shape mean?
Morphology
38
Teeth mature _________ (direction)
anterior to posterior
39
_____ teeth mature slightly ahead of ______ teeth
Mandibular Maxillary
40
What is a succedaneous tooth?
a permanent tooth that replaces a primary tooth
41
Most permanent develop off the primary tooth dental lamina. What is the first and last? What is the exception?
42
What are the stages of odontogenesis?
43
_______ determines the site of the tooth
Dental epithelium - then transfers this potential to ectomesenchyme
44
What are the characteristic events of the initiation stage?
45
Where does the dental lamina and vestible form in the mouth?
Lamina = lingually Vestibule = labially/bucally
46
The dental lamina indicates initial __________
site of each tooth bud
47
_______ determines tooth type
Ectomesenchyme!!!!
48
How do teeth know where to form?
Based on spatially arranged regulatory signaling
49
What do the oral ectoderm and dental ectoderm give rise to respectively?
50
Stages of Development: Bud Stage What is the functional stage and morphological appearance?
51
What is happening in the transition from the bud to the cap stage?
52
Stages of Development: Cap Stage What is the functional stage and morphological appearance?
53
_________ directs the folding and shape changes of the enamel organ.
Ectomesenchyme - shape of the tooth is set during this stage (morphogenesis)
54
In what stage is the shape of the tooth set?
Cap Stage
55
Characteristic events of Early Cap Stage
56
Where does the enamel knot appear first?
Early Cap Stage - (more visible in late cap)
57
Dental epithelium aggregates to form _________
enamel knot
58
Key roles of the enamel knot
59
What is the functional stage and morphological appearance of the bell stage?
60
In what stage does cytodifferentiation occur?
Bell Stage
61
What are the four layers of epithelium formed from cytodifferentiation of the enamel organ?
62
What are the characteristic events of the early bell stage?
- the cervical loop is visible - dental papilla begins differentiating into pre-odontoblasts - secondary enamel knot appears (only in multi-cusped teeth)
63
What are the characteristic events of Late Bell Stage?
- cusp formation
64
Image - Stages of Tooth Development

Sp24 - Oral Histology and Embryology (8 decks)

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