Dyspepsia and Peptic Ulcer

Question 1

How is H.Pylori diagnosed?

Answer 1

gastric biopsy        - urease test
			     - histology
			      - culture/sensitivity
urease breath test
FAT (faecal antigen test)
serology (IgA antibodies) - not accurate with increasing patient age

Question 2

How are peptic ulcers treated?

Answer 2

PPIs

H.Pylori testing and eradication therapy

Question 3

What is the triple therapy used for H.Pylori eradication?

Answer 3

PPI + amoxycillin 1g bd + clarithromycin 500mg bd

PPI + metronidazole 400mg bd + clarithromycin 250mg bd