Dysmenorrhea Flashcards
In which ages does dysmenorrhea peak?
Ages 19-24 years
What is primary dysmenorrhea?
It is severe painful colicky, cramp like spasmosdic pain in the lower abdomen associated with menstruation in the absence of an organic pathology
-it can present with nausea, vomiting, dizziness, headaches and sometimes syncope
What is secondary dysmenorrhea?
It is severe pain presenting with menstruation with a secondary pathology
What is the pathophysiology of primary dysmenorrhea?
Prostaglandins are released(PGF2 alpha) which causes myometrial vasoconstriction and uterine ischaemia
Type c afferent pain neurons are stimulated which causes spasmodic pain
What causes the pain in primary dysmenorrhea?
- Uterine ischaemia
- Uterine contractions
- Prostaglandin
What are the risk factors for primary dysmenorrhea?
- Early age of menarche
- Smoking
- Nulliparity
- Long and heavy menstrual flow
- Strong family history (where mom and sisters had dysmenorrhea)
- High levels of stress or anxiety or depression
- Young between 19 and 24 years
What are the clinical features of primary dysmenorrhea?
- Cramping, spasmosdic pain in the lower abdomen radiating to the back and inner thighs
- Nausea, vomiting, headache, syncope, diarrhea
What is the grading system that we use for primary dysmenorrhea?
Grade 0- not painful, no disruption of normal activities and no analgesia needed
Grade 1- mild pain, mild affects day top day life, rarely needed
Grade 2- painful, needs analgesia and affects day activities
Grade 3- severe pain(vegetative, nausea, vomiting), and poor effect of analgesia
What special investigations do we do in these patients?
Abdominal ultrasound to exclude pathology and if worried about ectopic pregnancy do b-hCG
What are the 3 ways to manage dysmenorrhea?
- Pharmacological
- Non-pharmacological
- Surgical
What are the pharmacological choices for dysmenorrhea?
- NSAIDS(inhibit prostaglandin synthesis)
- ibuprofen 400-800mg 6hourly
- mefenamic acid 250-500mg 6 hourly - Combination oral contraceptives
- Mirena
What are the non-pharmacological management options?
- Heat therapy-heat patches, hot water bottle
- Acupuncture
- TENS-Transcutaneous electrical nerve stimulation
What surgical treatment can we do for patients with primary dysmenorrhea?
- LUNA-laparoscopic uterosacral nerve ablation
2. Pre-sacral neurectomy
What supplements can we give to the patients?
- Vitamin B12
- Thiamine
- Magnesium
- Vitamin E
- Omega 3 fatty acid
- Transdermal nitroglycerin
What is the clinical presentation of dysmenorrhea?
- Pain is constant or diffuse and precedes menses by several days and can last through the menstrualk period
2.