Dypyridamole Flashcards
1
Q
Uses • ACS • Coronary artery stenting • Hypertension • Cerebrovascular TIA, stroke • AF • Myocardial perfusion scan • Cardio, cerebo peripheral arterial disease
A
- Cerebrovascular TIA, stroke
* Myocardial perfusion scan
2
Q
MOA • Increases cAMP • Block adenosine • Irreversibly inhibits COX • Prevent platelet aggregation • Decrease platelet aggregation • Irreversible binding to ADP • Block adenosine cellular uptake
A
- Increases cAMP
- Prevent platelet aggregation
- Block adenosine cellular uptake
3
Q
SE • Headache, flushing dizziness • GI upset • GI ulcer/ haemorrhage/ disturbance • Headache, flushing dizziness • Tinnitus • Bronchospasm • Thrombocytopaenia
A
- Headache, flushing dizziness
- GI upset
- Thrombocytopaenia
4
Q
Warning • Active bleeding • 3rd trimester of pregnancy • Ischaemic heart disease • Aortic stenosis • HF • Gout • Peptic ulceration • Renal impairment
A
- Ischaemic heart disease
- Aortic stenosis
- HF
5
Q
Interactions • Anticoagulants • Erythromycin • Antiplatelets • Adenosine • CCB • Cytochrome p450
A
- Anticoagulants
- Antiplatelets
- Adenosine
