Diuretics - potassium sparing Flashcards

1
Q
Name the potassium sparing diuretics
•	Furosemide
•	Co-amilozide
•	Co-amilofruse
•	Co-amiloride 
•	Bendroflumethiazide 
•	A,b,c
A

• A,b,c

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2
Q
Uses of potassium sparing diuretics 
•	Oedema 
•	Hypokalaemia 
•	Hypertension 
•	Hypotension
A

• Hypokalaemia

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3
Q
MOA of diuretics 
•	Weak diuretics on its own
•	Combine with another diuretic 
•	Inhibit Na, K, Cl at convoluted tube
•	Counteract potassium loss 
•	Act on convoluted tubules in kidney
•	Prevents absorption of sodium
•	Inhibit Na reabsorption 
•	Sodium and water excretion
•	Potassium excretion
•	Potassium retention
A
  • Weak diuretics on its own
  • Combine with another diuretic
  • Counteract potassium loss
  • Act on convoluted tubules in kidney
  • Inhibit Na reabsorption
  • Sodium and water excretion
  • Potassium retention
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4
Q
SE
•	Gout
•	Hypotension
•	Hypovolaemia
•	GI disturbance 
•	Electrolyte disturbance 
•	Urinary symptoms
A
SE
•	Hypotension
•	GI disturbance 
•	Electrolyte disturbance 
•	Urinary symptoms
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5
Q
WARNINGS
•	Severe renal impairment
•	Hyponatraemia
•	Hypokalaemia
•	Hyperkalaemia
•	Volume depletion
A
WARNINGS
•	Severe renal impairment
•	Hypokalaemia
•	Hyperkalaemia
•	Volume depletion
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6
Q
Interactions
•	NSAIDs
•	Potassium elevating drugs 
•	Aldosterone antagonist
•	Digoxin
•	Loop diuretics
•	lithium
A
  • Potassium elevating drugs
  • Aldosterone antagonist
  • Digoxin
  • lithium
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